Recombinant Human C10orf47 Protein

C10orf47. also known as chromosome 10 open reading frame 47. is a poorly characterized human protein encoded by the gene located at 10q22.1. Its biological function remains largely unknown due to limited experimental studies. Bioinformatics analyses suggest it may play roles in cellular processes such as proliferation or differentiation, though these predictions lack empirical validation. The protein is predicted to contain multiple phosphorylation sites and intrinsically disordered regions, hinting at potential involvement in signaling pathways or protein interactions.

C10orf47 has drawn attention in cancer research as genomic databases indicate altered expression in certain tumors, including breast and gastric cancers, though mechanistic links are unconfirmed. Recombinant versions of C10orf47 (produced via bacterial or mammalian expression systems) are primarily used as tools for antibody production, interaction studies, or preliminary functional assays. Current challenges in characterizing this protein stem from its low basal expression levels and absence of conserved domains with known molecular functions. Efforts to elucidate its role often combine recombinant protein studies with omics-based approaches, aiming to map interaction networks or identify associated pathways. Further investigation is needed to clarify its physiological significance and potential relevance to human diseases.