关键信息
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基因名
EPHA4
- 应用
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别名
EPHA4；HEK8；Ephrin type-A receptor 4
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q03137
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表达区间
570-986aa
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分子量
46 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, 5% Trehalose
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
EPHA4 (Ephrin type-A receptor 4) is a member of the Eph family of receptor tyrosine kinases, which play crucial roles in various physiological and pathological processes, including cell signaling, tissue development, and neuronal connectivity. Research has indicated that EPHA4 is involved in the regulation of cell migration, adhesion, and differentiation, making it a significant player in developmental biology and cellular communication. Dysregulation of EPHA4 has been linked to several diseases, including cancer, where it may contribute to tumor growth and metastasis, as well as neurological disorders, where it can affect synaptic plasticity and cognitive function. The production of recombinant EPHA4 protein has become a valuable tool for studying its structure, function, and interactions. By using techniques such as recombinant DNA technology, researchers can generate EPHA4 in a controlled environment, allowing for detailed investigations into its biological roles and therapeutic potential. Furthermore, understanding the signaling pathways mediated by EPHA4 may uncover novel targets for drug development, particularly in cancer therapy and neuroprotection. This research not only contributes to our foundational knowledge of cell signaling mechanics but also opens avenues for innovative treatments aimed at diseases where EPHA4 is implicated.
