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Rabbit Polyclonal SOX15 Antibody

  • 中文名: SOX15抗体
  • 别    名: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27
货号: IPDX34097
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/500 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

参考文献

以下是关于SOX15抗体的模拟参考文献示例(仅供格式参考,具体文献需通过学术数据库验证):

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1. **文献名称**: *"SOX15 regulates differentiation in human pluripotent stem cells via Wnt signaling"*

**作者**: Smith A, et al.

**摘要**: 本研究利用SOX15特异性抗体,通过免疫荧光和Western blot分析,揭示了SOX15在人多能干细胞神经分化过程中调控Wnt通路的关键作用,表明其可作为干细胞分化的生物标志物。

2. **文献名称**: *"Expression profiling of SOX15 in pancreatic cancer and its clinical implications"*

**作者**: Chen L, et al.

**摘要**: 通过免疫组化(使用兔源SOX15抗体)分析胰腺癌组织样本,发现SOX15高表达与患者预后不良相关,提示其可能作为潜在的肿瘤进展预测因子。

3. **文献名称**: *"Development and validation of a monoclonal antibody for murine SOX15 in embryonic development"*

**作者**: Tanaka K, et al.

**摘要**: 报道了一种新型小鼠SOX15单克隆抗体的开发,并通过免疫沉淀和染色质分析验证其特异性,证明SOX15在胚胎体节形成中调控肌源性分化。

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**建议查询方式**:

- 使用PubMed或Google Scholar搜索关键词:`SOX15 antibody`、`SOX15 immunohistochemistry`、`SOX15 function`。

- 筛选近年文献(如2020年后)以获取最新进展。

- 关注《Developmental Biology》《Oncotarget》等期刊相关领域研究。

请根据实际研究需求进一步验证文献真实性及细节。

背景信息

The SOX15 antibody is a crucial tool in studying the SOX (SRY-related HMG-box) family of transcription factors, which play pivotal roles in embryonic development, cell differentiation, and tissue homeostasis. SOX15. a member of the SOX gene group, is specifically associated with the regulation of stem cell pluripotency, myogenesis, and neurogenesis. Although less characterized than other SOX proteins (e.g., SOX2. SOX9), SOX15 is implicated in maintaining progenitor cell states and modulating differentiation pathways. Antibodies targeting SOX15 enable researchers to detect and quantify its expression in various biological samples, facilitating investigations into its functional mechanisms. These antibodies are widely used in techniques such as Western blotting, immunohistochemistry, and immunofluorescence to map SOX15 localization and dynamics in tissues or cultured cells. Given SOX15's potential involvement in diseases like cancer—where its dysregulation may influence tumor progression or stemness—the antibody also holds diagnostic and therapeutic research relevance. Validation of SOX15 antibodies includes specificity checks via knockout controls and cross-reactivity assessments to distinguish them from homologous SOX proteins. As research advances, SOX15 antibodies remain essential for unraveling its biological significance and translational applications.

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