| WB | 1/1000-1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 51Q1, OR51Q1 |
| Entrez GeneID | 390061 |
| WB Predicted band size | 35.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR51Q1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-62 amino acids from the N-terminal region of human OR51Q1. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于OR51Q1 (N-term)抗体的假设性参考文献示例(仅供参考，实际文献可能需要进一步检索验证)：
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1. **文献名称**: *"Characterization of Olfactory Receptor OR51Q1 Expression in Human Tissues Using a Novel N-Terminal Specific Antibody"*
**作者**: Smith A, et al. (2020)
**摘要**: 本研究开发了一种针对OR51Q1 N端表位的多克隆抗体，通过免疫组化和Western blot验证其在人嗅觉上皮组织中的特异性表达，并发现其在部分非嗅觉组织(如肺和前列腺)中的低水平表达，提示潜在非嗅觉功能。
2. **文献名称**: *"OR51Q1 Antibody Localizes to Cilia of Olfactory Sensory Neurons: Implications for Odorant Signaling"*
**作者**: Lee J, et al. (2018)
**摘要**: 利用抗OR51Q1 N端抗体进行免疫荧光染色，证实该受体定位于嗅觉神经元纤毛膜，并通过基因敲除实验揭示其参与特定挥发性有机分子的信号转导。
3. **文献名称**: *"A Comparative Study of Commercial Antibodies Targeting Olfactory Receptors: Validation of OR51Q1 as a Biomarker in Breast Cancer"*
**作者**: Chen X, et al. (2021)
**摘要**: 评估了多种商业OR51Q1抗体的特异性，发现N端抗体在乳腺癌细胞系中检测到异常表达，提示OR51Q1可能作为癌症诊断的潜在标志物。
4. **文献名称**: *"Antibody Cross-Reactivity in Olfactory Receptor Research: Challenges with OR51Q1 N-Terminal Reagents"*
**作者**: García R, et al. (2019)
**摘要**: 分析OR51Q1 N端抗体的交叉反应性，指出部分抗体可能与其他GPCRs发生非特异性结合，强调验证步骤在嗅觉受体研究中的必要性。
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**注意**：以上文献为模拟示例，实际引用需通过学术数据库(如PubMed、Web of Science)检索确认。若研究较少，可扩展至嗅觉受体家族或抗体开发方法学的相关论文。
The OR51Q1 (N-term) antibody is a specialized tool designed to target the N-terminal region of the olfactory receptor 51Q1 (OR51Q1), a member of the olfactory receptor (OR) family. ORs are G protein-coupled receptors (GPCRs) primarily involved in detecting odorants and mediating olfactory signal transduction. OR51Q1. encoded by the OR51Q1 gene, is expressed in olfactory sensory neurons and may play a role in recognizing specific odorant molecules. Beyond the olfactory epithelium, some studies suggest its expression in non-olfactory tissues, though its physiological roles in these contexts remain less understood.
This antibody is commonly used in research applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to study OR51Q1’s expression, localization, and function. Its specificity for the N-terminal domain allows researchers to distinguish OR51Q1 from other closely related olfactory receptors, aiding in precise protein characterization. Validation typically includes reactivity assays using recombinant proteins or cell lysates expressing OR51Q1. as well as controls like knockout models to confirm minimal cross-reactivity.
Researchers utilize the OR51Q1 (N-term) antibody to explore sensory biology, neuronal signaling pathways, and potential roles of olfactory receptors in non-traditional contexts, such as tissue-specific physiological or pathological processes. Its development and optimization contribute to advancing studies on chemosensation, receptor-ligand interactions, and the broader functional diversity of ORs.
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