| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 2 homolog, Zfp-2, Zinc finger protein 751, ZFP2, ZNF751 |
| Entrez GeneID | 80108 |
| WB Predicted band size | 52.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This ZFP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 379-411 amino acids from human ZFP2. |
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以下是3-4条关于ZFP2抗体的参考文献示例(注：部分信息为模拟概括，实际文献需通过学术数据库核实)：
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1. **文献名称**: *ZFP2 regulates germ cell development in mouse testes*
**作者**: Marcho, C., et al.
**摘要**: 本研究利用ZFP2特异性抗体，通过免疫组化揭示了ZFP2蛋白在小鼠睾丸生殖细胞中的动态表达模式，证实其在精子发生早期阶段的转录调控作用。
2. **文献名称**: *ZFP2 maintains pluripotency in embryonic stem cells via epigenetic modulation*
**作者**: Smith, J.R., et al.
**摘要**: 通过Western blot和ChIP-seq实验(使用ZFP2抗体)，作者发现ZFP2通过结合多能性基因启动子区域，维持胚胎干细胞自我更新，敲除后导致分化增强。
3. **文献名称**: *ZFP2 overexpression correlates with poor prognosis in lung adenocarcinoma*
**作者**: Chen, L., et al.
**摘要**: 研究采用ZFP2抗体对肺癌组织进行免疫组化分析，发现ZFP2高表达与患者生存率下降相关，提示其作为潜在肿瘤标志物的可能性。
4. **文献名称**: *Production and validation of a polyclonal ZFP2 antibody for functional studies*
**作者**: Hernandez, K., et al.
**摘要**: 本文详细描述了兔源ZFP2多克隆抗体的制备流程，并通过敲除细胞系验证其特异性，为后续ZFP2蛋白定位及互作研究提供工具。
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建议通过 **PubMed/Google Scholar** 检索以上作者或关键词，获取真实文献数据。部分模拟内容可能与实际研究存在差异，请以实际论文为准。
The ZFP2 antibody is a tool used to study the zinc finger protein 2 (ZFP2), a member of the Krüppel-associated box (KRAB) domain-containing zinc finger protein (ZFP) family. ZFP2. also known as ZNF639. is encoded by the ZNF2 gene and functions as a transcription factor involved in regulating gene expression through DNA binding. Zinc finger proteins are characterized by tandem Cys₂-His₂ motifs that mediate sequence-specific interactions with nucleic acids. ZFP2 is implicated in embryonic development, cellular differentiation, and proliferation, though its exact biological roles remain less characterized compared to other ZFPs.
The ZFP2 antibody is typically generated using immunogenic peptides or recombinant proteins derived from ZFP2's conserved regions, enabling detection in techniques like Western blotting, immunofluorescence, or chromatin immunoprecipitation (ChIP). It aids in elucidating ZFP2's expression patterns, subcellular localization, and interactions with target genes or proteins. Research has explored its potential roles in cancer, stem cell regulation, and epigenetic modulation, particularly through KRAB domain-mediated recruitment of co-repressors. Commercial ZFP2 antibodies are validated for specificity and affinity across species (e.g., human, mouse), though cross-reactivity may vary. Continued studies using this antibody could clarify ZFP2's contributions to developmental pathways and disease mechanisms, enhancing understanding of the KRAB-ZFP family's regulatory networks.
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