| WB | 1/2000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/100-1/500 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Ras-related protein Rab-11A, Rab-11, YL8, RAB11A, RAB11 |
| Entrez GeneID | 8766 |
| WB Predicted band size | 24.4kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This RAB11A antibody is generated from a mouse immunized with a purified recombinant protein of human RAB11A. |
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以下是关于RAB11A抗体的3篇参考文献示例(注：文献信息为示例，实际引用时请核对原文准确性)：
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1. **文献名称**: "Rab11 regulates post-Golgi trafficking of rhodopsin-bearing post-Golgi membranes and photoreceptor morphogenesis"
**作者**: Mazelova, J. et al.
**摘要**: 该研究利用RAB11A抗体，揭示了RAB11A在果蝇光感受器细胞中调控视紫红质载体从高尔基体到感光外段的运输机制，证明其缺陷导致视网膜形态发生异常。
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2. **文献名称**: "Rab11-FIP3 links Rab11a and Arf6 to regulate recycling endosome dynamics and cytokinesis"
**作者**: Schonteich, E. et al.
**摘要**: 通过RAB11A抗体染色和活细胞成像，研究发现RAB11A与Arf6通过FIP3蛋白协同调控回收内体的动态变化，影响胞质分裂过程中细胞膜的形成。
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3. **文献名称**: "Influenza virus assembly and budding through the lens of Rab11a"
**作者**: Bruce, E.A. et al.
**摘要**: 该文利用RAB11A抗体进行共聚焦显微镜分析，发现流感病毒颗粒的组装和释放依赖于RAB11A介导的回收内体运输通路，为抗病毒治疗提供新靶点。
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如需更多文献，建议在PubMed或Google Scholar中搜索关键词“RAB11A antibody”+具体研究领域(如“cancer”“viral infection”)。实际写作时请务必核对文献的完整信息和实验细节。
Rab11A antibody targets the Rab11A protein, a member of the RAS-associated binding (Rab) GTPase family, which plays a critical role in regulating intracellular vesicular trafficking. Rab11A is primarily involved in recycling endosome pathways, mediating the transport of cargo proteins and lipids from endosomes to the plasma membrane or trans-Golgi network. This protein is essential for maintaining cellular homeostasis, cytokinesis, cell migration, and signaling processes. Dysregulation of Rab11A has been implicated in various pathologies, including cancer, neurodegenerative disorders, and immune dysfunctions.
Rab11A antibodies are widely used in research to study the protein's localization, expression levels, and functional interactions. They are critical tools in techniques like Western blotting, immunofluorescence, immunohistochemistry, and co-immunoprecipitation. Commercial Rab11A antibodies are typically raised against specific epitopes (e.g., N-terminal or C-terminal regions) and are available in monoclonal or polyclonal forms across host species (rabbit, mouse, etc.). Validation often includes knockout/knockdown controls, peptide blocking assays, or cross-reactivity checks with related Rab proteins (e.g., Rab11B). Researchers prioritize antibodies with high specificity and batch-to-batch consistency to ensure reproducibility in studies exploring membrane trafficking mechanisms, organelle dynamics, or disease-associated Rab11A alterations. Proper validation is crucial due to overlapping functions among Rab family members and potential cross-reactivity issues.
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