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Rabbit Polyclonal DANREclvs2 Antibody

  • 中文名: DANRE clvs2抗体
  • 别    名: Clavesin-2, Retinaldehyde-binding protein 1-like 2, clvs2, rlbp1l2
货号: IPDX33374
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/2000 zebrafish
IF 咨询技术 zebrafish
IHC 咨询技术 zebrafish
ICC 技术咨询 zebrafish
FCM 咨询技术 zebrafish
Elisa 咨询技术 zebrafish

产品详情

AliasesClavesin-2, Retinaldehyde-binding protein 1-like 2, clvs2, rlbp1l2
Entrez GeneID566769
WB Predicted band size38.1kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivityzebrafish
ImmunogenThis DANRE clvs2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 262-295 amino acids from the C-terminal region of DANRE clvs2.

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参考文献

以下是关于斑马鱼(DANRE)**clvs2抗体**的示例参考文献(注:clvs2相关研究可能较少,以下为虚构示例,建议通过专业数据库进一步验证):

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1. **"Role of clvs2 in Zebrafish Somitogenesis: Antibody-Based Localization Study"**

*Author: Lee J, et al. (2020)*

*摘要*:利用DANRE clvs2特异性抗体进行免疫组化分析,揭示clvs2蛋白在斑马鱼体节形成期的梯度表达,提示其参与Notch信号通路的时空调控。

2. **"Functional Analysis of clvs2 in Early Embryonic Development of Danio rerio"**

*Author: Müller R, et al. (2018)*

*摘要*:通过CRISPR敲除结合clvs2抗体的Western blot验证,证明clvs2在斑马鱼原肠胚形成中调控细胞迁移,影响胚胎轴向发育。

3. **"clvs2 Antibody Validation for Zebrafish Neural Crest Studies"**

*Author: Chen X, et al. (2021)*

*摘要*:报道DANRE clvs2抗体的特异性验证,并应用于斑马鱼神经嵴细胞的免疫荧光成像,发现clvs2在神经嵴分化中的动态表达模式。

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**建议**:若需真实文献,可在PubMed或Google Scholar中检索关键词“Danio rerio clvs2 antibody”或“zebrafish clvs2 antibody”,并筛选近年研究。

背景信息

The DANRE clvs2 antibody is a specialized tool developed to study specific molecular processes in zebrafish (Danio rerio), a model organism widely used in developmental biology and genetics. This antibody targets the clvs2 protein, which is implicated in critical embryonic developmental stages, particularly during cleavage and early morphogenesis. The clvs2 gene is associated with cellular division, pattern formation, and signaling pathways that regulate axis specification and tissue differentiation in zebrafish embryos. Researchers utilize the DANRE clvs2 antibody to detect and localize the clvs2 protein in vivo, enabling insights into its spatial and temporal expression patterns during embryogenesis.

Produced typically in rabbits or mice through immunization with synthetic peptides or recombinant clvs2 protein, this antibody is validated for applications like Western blotting, immunohistochemistry, and immunofluorescence. Its development aligns with the growing need for precise molecular tools to dissect mechanisms underlying vertebrate development, particularly in the context of genetic or environmental disruptions. Studies employing the DANRE clvs2 antibody contribute to understanding congenital anomalies, regenerative processes, and evolutionary conservation of developmental pathways. By visualizing clvs2 dynamics, scientists aim to unravel its interactions with pathways like Wnt or Notch, offering broader implications for biomedical research, including tissue engineering and disease modeling.

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