Rabbit Polyclonal TAAR5 Antibody

TAAR5 (Trace Amine-Associated Receptor 5) is a G protein-coupled receptor (GPCR) belonging to the trace amine-associated receptor family, which detects endogenous trace amines and other volatile amine compounds. Primarily expressed in the olfactory epithelium, TAAR5 plays a role in detecting social cues, pheromones, and potentially noxious amines, contributing to chemosensory signaling. It is also found in brain regions, suggesting involvement in neuromodulation and behaviors linked to mood, cognition, and addiction. TAAR5 antibodies are immunological tools designed to detect, quantify, or inhibit TAAR5 protein expression in research settings. These antibodies are critical for studying TAAR5's localization, expression patterns, and functional roles in vitro and in vivo. Their applications include immunohistochemistry, Western blotting, and flow cytometry, aiding investigations into TAAR5's physiological relevance in olfaction, metabolic regulation, and neuropsychiatric disorders. Recent studies highlight TAAR5 as a potential therapeutic target for obesity, depression, or metabolic syndromes, driving demand for high-specificity antibodies. However, challenges remain in ensuring antibody selectivity due to structural similarities among TAAR subtypes. Validated TAAR5 antibodies enable mechanistic insights into its signaling pathways and interactions with ligands, supporting drug discovery and translational research in neuroscience and endocrinology.