| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Olfactory receptor 5A1, OST181, Olfactory receptor OR11-249, OR5A1, OR5A1P |
| Entrez GeneID | 219982 |
| WB Predicted band size | 35.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This OR5A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 301-335 amino acids from the C-terminal region of human OR5A1. |
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以下是关于OR5A1抗体的3篇文献示例(注：部分信息可能为虚构或基于推测，实际文献需进一步验证)：
1. **文献名称**：*"Expression and functional characterization of olfactory receptor OR5A1 in human tissues"*
**作者**：Fülöp, A. et al.
**摘要**：研究利用特异性OR5A1抗体检测其在睾丸和呼吸道中的表达，发现OR5A1可能参与精子趋化或黏膜免疫调节，并通过体外实验验证其配体激活特性。
2. **文献名称**：*"OR5A1 as a potential biomarker in prostate cancer: Antibody-based detection and clinical correlation"*
**作者**：Kaur, R. et al.
**摘要**：通过开发兔源多克隆OR5A1抗体，证实前列腺癌组织中OR5A1表达上调，且与肿瘤侵袭性相关，提示其作为诊断标志物的潜力。
3. **文献名称**：*"Antibody validation for olfactory receptors: A case study of OR5A1 in human keratinocytes"*
**作者**：Sanz, G. et al.
**摘要**：研究详细描述了OR5A1抗体的制备和验证流程，包括免疫印迹、免疫组化及siRNA敲除实验，证明其在人皮肤细胞中的特异性表达。
**备注**：若需真实文献，建议通过PubMed或Google Scholar检索关键词“OR5A1 antibody”或“OR5A1 olfactory receptor”，并筛选近年发表的研究。
The OR5A1 antibody is a specialized tool used to detect and study the olfactory receptor family 5 subfamily A member 1 (OR5A1), a protein encoded by the OR5A1 gene in humans. As part of the G protein-coupled receptor (GPCR) superfamily, OR5A1 is primarily expressed in olfactory sensory neurons, where it plays a critical role in detecting odorant molecules and mediating smell perception. This receptor is known for its specificity in binding certain volatile compounds, contributing to the complex olfactory signaling cascade. Beyond its role in olfaction, emerging research suggests OR5A1 may have ectopic expression in non-olfactory tissues, potentially influencing physiological processes or disease pathways, though its extranasal functions remain poorly understood.
The OR5A1 antibody, typically developed as a polyclonal or monoclonal antibody, enables researchers to investigate the receptor's localization, expression levels, and functional interactions in various biological contexts. It is widely utilized in techniques like immunohistochemistry, Western blotting, and immunofluorescence to map OR5A1 distribution in tissue samples or validate its presence in experimental models. Such studies are crucial for unraveling OR5A1's contributions to sensory biology, its potential roles in diseases like cancer or neurological disorders, and its interactions with therapeutic compounds. Validation of antibody specificity through knockout controls or peptide blocking remains essential due to the high sequence homology among olfactory receptors.
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