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Rabbit Polyclonal (DANRE)fabp10a Antibody

  • 中文名： (DANRE) fabp10a抗体
  • 别    名： Fatty acid-binding protein 10-A, liver basic, Zf-FABP10, Zf-Lb-FABP, Fatty acid-binding protein, liver, Liver bile acid-binding protein, L-BABP, z-L-BABP, Liver-type fatty acid-binding protein, L-FABP, Liver-type FABP, fabp10a, fabp10
货号: IPDX32682
Price： ￥1180
数量：
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验证与应用

应用及物种
WB 1/1000 zebrafish
IF 咨询技术 zebrafish
IHC 咨询技术 zebrafish
ICC 技术咨询 zebrafish
FCM 咨询技术 zebrafish
Elisa 咨询技术 zebrafish

产品详情

AliasesFatty acid-binding protein 10-A, liver basic, Zf-FABP10, Zf-Lb-FABP, Fatty acid-binding protein, liver, Liver bile acid-binding protein, L-BABP, z-L-BABP, Liver-type fatty acid-binding protein, L-FABP, Liver-type FABP, fabp10a, fabp10
Entrez GeneID171481
WB Predicted band size14.0kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivityzebrafish
ImmunogenThis (DANRE) fabp10a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 47-80 amino acids of DANRE fabp10a.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是3篇关于斑马鱼(Danio rerio)fabp10a抗体的示例文献(注：文献为虚构示例，仅供参考结构与内容方向)：

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1. **文献名称**：*"Tissue-specific expression and regulation of fabp10a in zebrafish hepatic development"*

**作者**：Her GM, Deng JM, Chen JY

**摘要**：研究利用fabp10a抗体通过免疫组化和Western blot分析斑马鱼胚胎至成鱼阶段的肝脏发育，发现fabp10a在肝脏特异性表达，且其表达水平受脂肪酸代谢通路调控。

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2. **文献名称**：*"Fabp10a as a biomarker for chemical-induced hepatotoxicity in zebrafish larvae"*

**作者**：Li Z, Wang H, Liu S

**摘要**：通过抗体验证fabp10a在斑马鱼肝脏损伤模型中的表达变化，证明其抗体可用于定量检测化学毒素(如TCDD)暴露后的肝细胞功能异常。

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3. **文献名称**：*"Functional analysis of fabp10a knockout zebrafish using CRISPR/Cas9 and antibody-based validation"*

**作者**：Kurokawa T, Unal E, Rothenberg ME

**摘要**：研究通过CRISPR敲除fabp10a基因，并利用特异性抗体证实蛋白表达缺失，发现突变体出现肝脏脂肪代谢紊乱和胆汁淤积表型。

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**提示**：实际文献需通过数据库(如PubMed、Google Scholar)以关键词“fabp10a antibody Danio rerio”检索。建议结合实验目的(如发育、代谢、毒理)筛选相关研究。

背景信息

The DANRE (Danio rerio) fabp10a antibody is a critical tool for studying lipid metabolism and liver development in zebrafish. FABP10a, also known as liver-type fatty acid-binding protein (L-FABP), is a highly conserved protein involved in intracellular fatty acid transport, lipid homeostasis, and peroxisome proliferation. In zebrafish, fabp10a is predominantly expressed in hepatocytes and plays a vital role during liver organogenesis, making it a valuable marker for hepatic research. This antibody is widely used to detect FABP10a expression in immunoassays such as Western blotting, immunohistochemistry, and immunofluorescence, enabling researchers to visualize liver morphology, assess hepatocyte differentiation, and investigate metabolic disorders. Its specificity for zebrafish FABP10a minimizes cross-reactivity with other FABP isoforms, ensuring reliable results. Studies employing this antibody have contributed to understanding liver regeneration, non-alcoholic fatty liver disease (NAFLD) models, and chemical-induced hepatotoxicity in zebrafish. Additionally, it aids in comparative studies exploring evolutionary conservation of lipid metabolism pathways between zebrafish and mammals. Developed and validated for zebrafish models, the DANRE fabp10a antibody remains essential for developmental biology, toxicology, and metabolic disease research.

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