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Rabbit Polyclonal OVOS1 Antibody

  • 中文名: OVOS1抗体
  • 别    名: Ovostatin homolog 1, OVOS1
货号: IPDX32677
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesOvostatin homolog 1, OVOS1
WB Predicted band size134.5kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis OVOS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 561-595 amino acids from the Central region of human OVOS1.

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参考文献

以下是关于OVOS1抗体的3篇模拟参考文献示例(基于学术文献常见结构整理,非真实文献):

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1. **文献名称**:*OVOS1 Antibody Development and Its Application in Ovarian Cancer Biomarker Discovery*

**作者**:Smith J, et al.

**摘要**:本研究开发了一种针对OVOS1蛋白的高特异性单克隆抗体,并验证了其在卵巢癌组织中的表达水平。通过免疫组化分析发现,OVOS1在晚期卵巢癌中显著上调,提示其可能作为潜在的诊断标志物或治疗靶点。

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2. **文献名称**:*Characterization of OVOS1 in Mammalian Gametogenesis Using Polyclonal Antibodies*

**作者**:Li Y, et al.

**摘要**:研究利用兔源多克隆抗体探究OVOS1在小鼠生殖细胞发育中的功能。Western blot和免疫荧光结果显示,OVOS1在卵母细胞成熟过程中动态表达,可能参与调控减数分裂进程。

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3. **文献名称**:*OVOS1 as a Novel Target in Triple-Negative Breast Cancer: Insights from Antibody-Based Inhibition Studies*

**作者**:Garcia R, et al.

**摘要**:通过抗OVOS1抗体阻断实验,发现抑制OVOS1可显著降低三阴性乳腺癌细胞的迁移和侵袭能力,表明OVOS1在肿瘤转移中起关键作用,为开发靶向疗法提供了实验依据。

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**备注**:以上为模拟文献,实际研究请通过PubMed、Web of Science等数据库检索最新成果。

背景信息

OVOS antibody targets the OVOS1 (Oviductal Secretory Protein 1) protein, a glycoprotein predominantly expressed in the female reproductive tract, particularly the oviduct. First identified in mammals, OVOS1 is implicated in early reproductive processes, including oocyte maturation, fertilization, and embryo development. It belongs to the lipocalin protein family and may function in molecular transport or immune modulation within the oviductal microenvironment. Structurally, OVOS1 contains conserved domains associated with ligand binding, suggesting roles in interacting with gametes or early embryos.

Research on OVOS antibodies has focused on their utility in studying female fertility and reproductive pathologies. These antibodies enable detection of OVOS1 in tissue samples (e.g., via immunohistochemistry or Western blot) and help elucidate its spatial-temporal expression patterns. Aberrant OVOS1 levels have been linked to conditions like ectopic pregnancy and oviductal inflammation, positioning it as a potential biomarker. Additionally, OVOS antibodies are tools for exploring assisted reproductive technologies, as OVOS1 may influence embryo quality. Current studies also investigate its relevance in certain cancers, particularly gynecological malignancies. Commercial OVOS antibodies are typically raised in rabbits or mice, with validation in species-specific models.

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