Rabbit Polyclonal ZNF830 Antibody

The ZNF830 antibody is a research tool designed to detect and study the zinc finger protein 830 (ZNF830), a member of the zinc finger protein family characterized by conserved C2H2-type zinc finger domains. ZNF830 is implicated in DNA damage response pathways, particularly in homologous recombination repair, where it interacts with key proteins like BRCA1 to maintain genomic stability. Dysregulation of ZNF830 has been linked to cancer progression, especially in BRCA1-deficient malignancies, making it a potential biomarker or therapeutic target. The antibody is commonly used in techniques such as Western blotting, immunoprecipitation, and immunofluorescence to investigate ZNF830's expression patterns, subcellular localization, and protein-protein interactions. Most commercially available ZNF830 antibodies are produced in rabbit or mouse hosts, with validation in specific cell lines or tissues. Researchers utilize this reagent to explore ZNF830's role in DNA repair mechanisms, its involvement in carcinogenesis, and its relationship with cancer-associated pathways. Current studies focus on its diagnostic relevance in breast and ovarian cancers, as well as its functional crosstalk with other DNA repair factors. Proper validation of antibody specificity through knockout controls remains critical for reliable experimental outcomes.