关键信息
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基因名
CEP63
- 应用
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别名
CEP63Centrosomal protein of 63 kDa; Cep63
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96MT8
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表达区间
1-495aa
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分子量
73.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CEP63 (Centrosomal Protein 63) is a pivotal protein that plays a crucial role in centrosome function and cell division. It is primarily implicated in the regulation of centriole biogenesis and the maintenance of centrosome integrity. Disruptions in CEP63 function have been associated with various cellular malfunctions, notably in the context of cancer and developmental disorders. Recent studies have highlighted its significance in the formation and organization of microtubules, which are essential for mitotic spindle assembly and proper chromosome segregation during cell division. Given the importance of centrosomes in cellular homeostasis, the investigation of CEP63 has garnered substantial interest within the fields of cell biology and oncology. Researchers have begun to explore the potential of CEP63 as a novel biomarker for cancer progression and as a target for therapeutic interventions. The recombinant protein expression of CEP63 allows for in-depth structural and functional studies, contributing to our understanding of its molecular mechanisms. This research not only aids in deciphering the complexities of cell cycle regulation but also has implications for developing strategies to combat cancerous growths, where centrosome abnormalities are prevalent. Understanding CEP63's role and its surrounding pathways could pave the way for innovative approaches in treating diseases linked to malfunctioning centrosomes. Thus, the study of CEP63 recombinant protein remains a critical area of investigation with the potential to unlock new avenues in biomedical research.
