关键信息
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基因名
F2RL2
- 应用
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别名
(PAR-3)(Coagulation factor II receptor-like 2)(Thrombin receptor-like 2)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00254
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表达区间
39-374aa
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分子量
40.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
F2RL2, also known as protease-activated receptor 2 (PAR2), is a member of the G protein-coupled receptor family, playing a pivotal role in various physiological and pathological processes. Activated by serine proteases, F2RL2 is involved in mediating inflammatory responses, pain perception, and tissue repair mechanisms. Its dysregulation has been implicated in a range of diseases, including asthma, chronic pain, and cancer, making it an attractive therapeutic target. Recent research has focused on the recombinant production of F2RL2 to gain insights into its structure-function relationships and to develop potential pharmacological interventions. By producing F2RL2 as a recombinant protein, researchers can investigate its activation mechanisms, downstream signaling pathways, and interactions with other proteins. This understanding may lead to the design of specific inhibitors or agonists, which could offer new avenues for treating diseases associated with F2RL2 dysregulation. Furthermore, the recombinant F2RL2 can serve as a valuable tool in drug discovery and development processes, enhancing our understanding of its biological functions and therapeutic potential. Overall, the study of F2RL2 recombinant protein is an essential step toward elucidating its role in health and disease, ultimately contributing to the development of targeted therapies.
