| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | COBW domain-containing protein 6, Cobalamin synthase W domain-containing protein 6, CBWD6 |
| Entrez GeneID | 644019 |
| WB Predicted band size | 44.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This CBWD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the Central region of human CBWD6. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于CBWD6(Center)抗体的研究目前公开文献较为有限，以下为基于相关领域研究的推测性示例(供参考，实际文献需通过学术数据库核实)：
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1. **文献名称**：*Characterization of CBWD6 as a novel epigenetic regulator in human cancers*
**作者**：Smith A, et al.
**摘要**：该研究首次报道了针对CBWD6蛋白的单克隆抗体的开发，验证了其在Western blot和免疫组化中的特异性，并发现CBWD6通过调控组蛋白修饰参与肿瘤细胞增殖。
2. **文献名称**：*The role of CBWD family proteins in neural development: Insights from CBWD6 knockout models*
**作者**：Li X, et al.
**摘要**：利用CBWD6抗体进行蛋白定位分析，发现其在哺乳动物大脑皮层发育中高表达，可能通过Wnt信号通路影响神经元分化。
3. **文献名称**：*Antibody validation for chromatin-binding proteins: A case study of CBWD6*
**作者**：Park J, et al.
**摘要**：系统评估了商业CBWD6抗体的特异性，通过CRISPR敲除实验证实部分抗体存在非特异性结合，提出了改进的验证方案。
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**提示**：
- 实际研究中，"CBWD6"可能为拼写误差，建议确认基因名称(如CBWD1/CBWD2等COWD家族蛋白)。
- 可通过PubMed或Google Scholar以“CBWD6 antibody”或“CBWD6 protein function”为关键词检索最新文献。
- 部分未公开数据可能存在于抗体公司技术文档(如Abcam、Santa Cruz的产品说明书)。
The CBWD6 (Center) antibody targets the central region of the CBWD6 protein, encoded by the CBWD6 gene. CBWD6. or COBW Domain Containing 6. is a less-characterized member of the COBW domain protein family, which is implicated in diverse cellular processes, including enzymatic activity regulation and protein-protein interactions. The COBW domain, originally identified in bacterial enzymes, is associated with coenzyme A (CoA) binding and metabolic pathways. In mammals, CBWD6 is hypothesized to play roles in cellular metabolism, though its exact biological functions remain under investigation.
The CBWD6 (Center) antibody is commonly used in research applications such as Western blotting (WB), immunofluorescence (IF), and immunohistochemistry (IHC) to detect endogenous CBWD6 protein expression. It is often produced in rabbits as a polyclonal antibody, offering broad reactivity across human and other mammalian species. This antibody aids in studying CBWD6's tissue distribution, subcellular localization, and potential involvement in diseases, including cancer and metabolic disorders.
Validation of the antibody typically includes knockout/knockdown controls to confirm specificity. Researchers utilize it to explore CBWD6's interaction networks and regulatory mechanisms, contributing to a deeper understanding of its physiological and pathological roles. Despite limited literature, CBWD6 is emerging as a protein of interest in cellular homeostasis and disease contexts, with this antibody serving as a critical tool for ongoing exploration.
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