| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Protein phosphatase 1 regulatory subunit 7, Protein phosphatase 1 regulatory subunit 22, PPP1R7, SDS22 |
| Entrez GeneID | 5510 |
| WB Predicted band size | 41.6kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse |
| Immunogen | This PPP1R7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-340 amino acids from the C-terminal region of human PPP1R7. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是几篇关于PPP1R7抗体的模拟参考文献示例(注：以下内容为虚构，仅供格式参考，建议通过学术数据库查询真实文献)：
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1. **文献名称**：*Characterization of PPP1R7 Antibody in Cell Cycle Regulation*
**作者**：Smith A, et al.
**摘要**：研究通过Western blot和免疫荧光技术验证了PPP1R7抗体的特异性，发现PPP1R7在细胞周期G2/M期调控中与蛋白磷酸酶1(PP1)相互作用，影响有丝分裂进程。
2. **文献名称**：*PPP1R7 Expression and Antibody Validation in Cancer Models*
**作者**：Lee J, et al.
**摘要**：开发了一种高特异性PPP1R7单克隆抗体，用于检测其在乳腺癌细胞系中的表达水平，发现PPP1R7低表达与肿瘤细胞异常增殖相关。
3. **文献名称**：*Role of PPP1R7 in Neuronal Development: Insights from Antibody-Based Assays*
**作者**：Garcia R, et al.
**摘要**：利用PPP1R7多克隆抗体研究其在小鼠脑组织中的分布，揭示其在神经元突触形成中可能通过PP1信号通路调节突触可塑性。
4. **文献名称**：*PPP1R7 Antibody Application in Protein-Protein Interaction Studies*
**作者**：Chen L, et al.
**摘要**：通过免疫共沉淀(Co-IP)结合质谱分析，鉴定了PPP1R7与多个细胞骨架蛋白的相互作用，抗体被用于验证其在细胞迁移中的功能。
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**注意**：以上文献为示例性质，实际研究需参考真实发表的论文。建议通过PubMed、Google Scholar等平台检索关键词“PPP1R7 antibody”或“PPP1R7 function”获取最新进展。
The PPP1R7 (Protein Phosphatase 1 Regulatory Subunit 7) antibody is a tool used to detect and study the PPP1R7 protein, a regulatory component of protein phosphatase 1 (PP1). PP1 is a serine/threonine phosphatase critical for dephosphorylation events in cellular processes like cell cycle progression, metabolism, and signal transduction. PPP1R7. also known as SDS22 in some contexts, functions as a regulatory subunit that modulates PP1 activity, substrate specificity, and localization. It plays a role in maintaining PP1 stability and facilitating interactions with target proteins, particularly during mitosis and chromosome segregation.
Antibodies against PPP1R7 are essential for investigating its expression, localization, and function in various tissues and disease models. They are commonly used in techniques such as Western blotting, immunoprecipitation, and immunofluorescence. Research involving PPP1R7 antibodies has shed light on its involvement in cell cycle regulation, DNA damage response, and potential links to cancer, where dysregulated PP1 activity may contribute to tumorigenesis. These antibodies are typically validated for specificity and cross-reactivity across species, such as human, mouse, and rat. Understanding PPP1R7's role through antibody-based studies provides insights into phosphatase-mediated regulatory mechanisms and their implications in health and disease.
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