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Rabbit Polyclonal SDR39U1(N-term) Antibody

  • 中文名: SDR39U1 (N-term)抗体
  • 别    名: Epimerase family protein SDR39U1, 111-, Short-chain dehydrogenase/reductase family 39U member 1, SDR39U1, C14orf124, HCDI
货号: IPDX31958
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesEpimerase family protein SDR39U1, 111-, Short-chain dehydrogenase/reductase family 39U member 1, SDR39U1, C14orf124, HCDI
Entrez GeneID56948
WB Predicted band size31.1kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis SDR39U1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-103 amino acids from the N-terminal region of human SDR39U1.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于SDR39U1(N-term)抗体的3篇虚构示例参考文献(注:以下内容为模拟生成,实际文献需通过学术数据库验证):

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1. **文献名称**: "Characterization of SDR39U1 in Lipid Metabolism via a Novel Polyclonal Antibody"

**作者**: Zhang L, et al.

**摘要**: 本研究通过免疫兔制备了针对SDR39U1 N端的多克隆抗体,验证了其在Western blot和免疫组化中的特异性。研究发现SDR39U1在肝脏组织中高表达,并参与调控脂肪酸氧化通路,为代谢疾病研究提供了工具。

2. **文献名称**: "SDR39U1 Antibody Validation and Its Role in Cancer Cell Proliferation"

**作者**: Kim S, et al.

**摘要**: 文章报道了一种商业化SDR39U1(N-term)抗体的验证数据(货号:ABX-2023),确认其可识别内源性蛋白。功能实验表明,SDR39U1通过影响Wnt/β-catenin信号通路促进结直肠癌细胞增殖。

3. **文献名称**: "Developmental Expression of SDR39U1 in Mouse Embryos Revealed by Immunostaining"

**作者**: Müller R, et al.

**摘要**: 利用SDR39U1 N端抗体进行小鼠胚胎组织免疫荧光分析,发现该蛋白在神经管和心脏发育阶段特异性高表达,提示其可能参与胚胎早期分化调控。

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如需实际文献,建议通过PubMed或Google Scholar以“SDR39U1 antibody”或“SDR short-chain dehydrogenase”为关键词检索,或联系抗体供应商(如Abcam、Santa Cruz)获取产品相关引用文献。

背景信息

The SDR39U1 (N-term) antibody is designed to target the N-terminal region of the SDR39U1 protein, a member of the short-chain dehydrogenase/reductase (SDR) superfamily. SDR enzymes are involved in diverse metabolic pathways, including steroidogenesis, lipid metabolism, and xenobiotic detoxification, utilizing NAD(H) or NADP(H) as cofactors. SDR39U1. though less characterized compared to other SDR members, is hypothesized to participate in redox reactions critical for cellular homeostasis. Its N-terminal domain may contribute to substrate binding or cofactor interaction, given conserved structural motifs in SDR proteins.

This antibody is commonly used in research to study SDR39U1 expression, localization, and function via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Specificity for the N-terminal region helps distinguish SDR39U1 from homologous SDR proteins, reducing cross-reactivity risks. Validation often includes knockout cell lines or siRNA knockdown to confirm target specificity.

Research applications focus on elucidating SDR39U1's role in metabolic disorders, cancer, or oxidative stress responses. However, detailed mechanistic insights remain limited, necessitating further investigation. The antibody serves as a critical tool for advancing understanding of SDR39U1's biological significance and potential therapeutic relevance.

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