| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Nucleosome assembly protein 1-like 2, Brain-specific protein, X-linked, NAP1L2, BPX |
| Entrez GeneID | 4674 |
| WB Predicted band size | 52.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This NAP1L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-139 amino acids from the N-terminal region of human NAP1L2. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于NAP1L2 (N-term)抗体的3篇模拟参考文献示例(内容为虚构，仅供参考)：
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1. **文献名称**: *"NAP1L2 regulates neural progenitor differentiation via chromatin remodeling"*
**作者**: Smith J, et al.
**摘要**: 本研究利用NAP1L2 (N-term)抗体通过Western blot和免疫荧光技术，揭示了NAP1L2在小鼠大脑皮层神经前体细胞分化中的关键作用。结果显示，NAP1L2通过调控组蛋白H2A/H2B的动态组装影响染色质可及性，从而参与神经发育障碍相关基因的表达。
2. **文献名称**: *"Expression profiling of NAP1L2 in hepatocellular carcinoma using a novel N-terminal specific antibody"*
**作者**: Chen L, et al.
**摘要**: 通过开发并验证一种高特异性的NAP1L2 (N-term)抗体，本研究在肝癌组织样本中检测到NAP1L2的异常高表达。免疫组化分析表明，其表达水平与肿瘤进展和患者预后显著相关，提示其作为潜在生物标志物的价值。
3. **文献名称**: *"Role of NAP1L2 in mouse embryonic stem cell pluripotency"*
**作者**: Tanaka K, et al.
**摘要**: 本研究使用NAP1L2 (N-term)抗体进行ChIP-seq分析，发现NAP1L2通过结合多能性基因(如Oct4、Nanog)的启动子区域维持胚胎干细胞的自我更新能力。敲低实验证实其缺失会导致多能性丧失。
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**注**: 以上文献为示例，实际引用时需通过PubMed、Google Scholar等平台检索真实发表的研究，并核实抗体货号(如Santa Cruz的sc-10039)及实验应用场景。
The NAP1L2 (N-term) antibody is a specialized tool designed to detect the N-terminal region of Nucleosome Assembly Protein 1-Like 2 (NAP1L2), a member of the nucleosome assembly protein (NAP) family. NAP1L2 is involved in chromatin remodeling and histone chaperone activity, playing a role in regulating DNA replication, transcription, and epigenetic modifications. It shares structural homology with other NAP family proteins but exhibits distinct tissue-specific expression patterns, with higher levels observed in the brain, particularly during neurodevelopment.
This antibody is commonly used in research applications such as Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to study NAP1L2's localization, expression dynamics, and interaction partners. Its specificity for the N-terminal region ensures recognition of full-length or truncated isoforms, aiding in functional studies. NAP1L2 has been implicated in neural progenitor cell proliferation, differentiation, and brain development, with potential links to neurodevelopmental disorders and cancer. The antibody's utility extends to investigating epigenetic regulation and cellular responses to DNA damage. Validation typically includes testing in knockout models or siRNA-treated cells to confirm target specificity. Researchers employ it to explore NAP1L2's role in chromatin organization and its crosstalk with signaling pathways in both physiological and pathological contexts.
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