| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 319, ZNF319, KIAA1388 |
| Entrez GeneID | 57567 |
| WB Predicted band size | 65.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ZNF319 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-532 amino acids from the C-terminal region of human ZNF319. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZNF319抗体的3篇参考文献示例(注：文献为虚构，仅用于示例用途)：
1. **文献名称**：*ZNF319 suppresses tumorigenesis in colorectal cancer by modulating Wnt/β-catenin signaling*
**作者**：Zhang Y, et al.
**摘要**：本研究通过ZNF319抗体进行免疫组化和Western blot分析，发现ZNF319在结直肠癌组织中表达下调，其缺失促进肿瘤细胞增殖和迁移。机制研究表明，ZNF319通过抑制Wnt/β-catenin信号通路发挥抑癌作用。
2. **文献名称**：*Characterization of ZNF319 as a novel regulator of DNA damage response*
**作者**：Li X, et al.
**摘要**：利用ZNF319抗体进行免疫荧光和ChIP-seq实验，揭示ZNF319在DNA损伤修复中的关键作用。研究发现ZNF319与ATM激酶相互作用，调控细胞周期检查点蛋白的稳定性。
3. **文献名称**：*ZNF319 expression correlates with immune infiltration in breast cancer*
**作者**：Wang H, et al.
**摘要**：通过ZNF319抗体检测乳腺癌组织微阵列，发现高表达ZNF319的患者肿瘤微环境中CD8+ T细胞浸润增加，提示其可能通过调节免疫应答影响乳腺癌预后。
(提示：实际文献需通过PubMed、Google Scholar等平台检索确认。)
ZNF319. a member of the zinc finger protein family, is characterized by its C2H2-type zinc finger domains, which facilitate DNA or RNA binding and participation in transcriptional regulation. Though its precise biological roles remain under investigation, ZNF319 is implicated in cellular processes such as differentiation, proliferation, and apoptosis. Studies suggest potential interactions with signaling pathways like Wnt/β-catenin or p53. hinting at roles in cancer development and stress response.
ZNF319 antibodies are immunological tools designed to detect and quantify the ZNF319 protein in experimental settings. These antibodies are typically produced in hosts like rabbits or mice using immunogenic peptide sequences derived from ZNF319. Validated for applications such as Western blotting, immunofluorescence, and immunohistochemistry, they aid in exploring ZNF319's expression patterns across tissues or its subcellular localization. Some antibodies are further verified via knockout controls to ensure specificity.
Research utilizing ZNF319 antibodies has linked the protein to diseases, including certain cancers, where its expression may correlate with tumor progression or patient prognosis. However, functional insights remain preliminary, necessitating further studies to clarify its mechanistic contributions. Commercial ZNF319 antibodies often include detailed validation data, enabling researchers to select reagents appropriate for their specific experimental needs. Overall, these antibodies serve as critical reagents for dissecting ZNF319's role in normal physiology and disease.
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