WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Differentially expressed in FDCP 6 homolog, DEF-6, IRF4-binding protein, DEF6, IBP |
Entrez GeneID | 50619 |
WB Predicted band size | 73.9kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是3篇关于DEF6抗体的示例参考文献(注:以下内容为模拟示例,非真实文献):
---
1. **标题**: *"DEF6 regulates T-cell synapse formation and immune activation through cytoskeletal remodeling"*
**作者**: Smith A, et al.
**摘要**: 研究使用DEF6特异性抗体探究其在T细胞突触形成中的作用,发现DEF6通过调控肌动蛋白重组促进免疫突触成熟,缺陷导致T细胞活化受损。
---
2. **标题**: *"Autoimmunity in DEF6-deficient mice correlates with altered B-cell signaling"*
**作者**: Chen L, et al.
**摘要**: 通过DEF6抗体检测基因敲除小鼠模型,发现DEF6缺失导致B细胞过度活化及自身抗体产生,提示其在抑制系统性自身免疫中的关键作用。
---
3. **标题**: *"Elevated DEF6 expression in lupus nephritis patients links to disease severity"*
**作者**: Gupta R, et al.
**摘要**: 利用DEF6抗体进行组织染色,发现系统性红斑狼疮(SLE)患者肾脏中DEF6蛋白表达升高,与炎症因子水平正相关,提示其作为疾病生物标志物的潜力。
---
4. **标题**: *"DEF6 interacts with SWAP-70 to modulate RAC1 signaling in dendritic cells"*
**作者**: Müller T, et al.
**摘要**: 通过免疫共沉淀(使用DEF6抗体)揭示DEF6与SWAP-70协同调控树突状细胞迁移的机制,为靶向免疫细胞迁移的治疗提供新思路。
---
(注:以上文献为模拟生成,实际研究中请通过学术数据库核实具体参考文献。)
×