关键信息
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基因名
PPP1R1C
- 应用
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别名
IPP5; Inhibitor-5 of protein phosphatase 1
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种属
Mouse
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8BKK4
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表达区间
Met1~Glu103
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分子量
44kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PPP1R1C, also known as Protein Phosphatase 1 Regulatory Subunit 1C, is a regulatory protein that plays a critical role in the modulation of protein phosphatase 1 (PP1) activity, which is essential for various cellular processes including cell division, differentiation, and apoptosis. Research into PPP1R1C has gained significant interest due to its involvement in numerous physiological and pathological conditions, such as cancer, neurodegenerative diseases, and cardiovascular disorders. The protein acts as an inhibitor of PP1, thereby influencing various signaling pathways crucial for cell function. Understanding the biochemical properties and interactions of PPP1R1C can provide insights into its regulatory mechanisms and potential implications in disease states. As a result, recombinant expression of PPP1R1C has become essential for elucidating its structural and functional characteristics, facilitating the development of targeted therapies. Advances in recombinant protein technology enable researchers to produce large quantities of pure PPP1R1C for biochemical assays and structural studies, paving the way for a deeper understanding of its role in cellular signaling and disease pathology. Overall, the study of PPP1R1C as a recombinant protein is a promising avenue for both basic and applied biomedical research, as it holds potential for therapeutic interventions aimed at modulating PP1 activity in various clinical contexts.
