| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ21901 |
| Uniprot No | Q53R41 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-847aa |
| 氨基酸序列 | MKKTPVFLESLVTNMLRLRAICPFSWRVFQFRPISCEPLIIQMNKCTDEEQMFGFIERNKAILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKLMNDDTLVNVLYVTQQFAGEAHDPLVEALVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVHRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERCNNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCNHPASFVKLFVALGPIAGPEEKKQLKSTMLLMSEDLTGEQALAVLGAMGDMESRNSCLIKRVTSVLHKHLDGYKPLELLKITQELTFLHFQRKEFFAKLRELLLSYLKNSFIPTEVSVLVRAISLLPSPHLDEVGISRIEAVLPQCDLNNLSSFATSVLRWIQHDHMYLDNMTAKQLKLLQKLDHYGRQRLQHSNSLDLLRKELKSLKGNTFPESLLEEMIATLQHFMDDINYINVGEIASFISSTDYLSTLLLDRIASVAVQQIEKIHPFTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILDPFILVFLGFSLATLEYFPEDLLKAIFNIKFLARLDSQLEILSPSRSARVQFHLMELNRSVCLECPEFQIPWFHDRFCQQYNKGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKRKKPLPYGSHNIALGQLPEMPWESNIEIVGSRLPPGAERIALEFLDSKALCRNIPHMKGKSAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIFGEVKSCL |
| 分子量 | 97.4 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人FLJ21901蛋白的3篇参考文献的简要整理(注：FLJ21901蛋白相关研究较少，可能存在更名或别名;以下内容为示例性虚构，建议根据实际研究补充)：
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1. **文献名称**：*Functional Characterization of Recombinant Human FLJ21901 Protein as a Novel Kinase Involved in Cell Proliferation*
**作者**：Zhang Y et al.
**摘要**：本研究成功在大肠杆菌系统中表达并纯化了重组人FLJ21901蛋白，发现其在体外具有激酶活性，并通过细胞实验表明该蛋白通过调控MAPK信号通路促进肿瘤细胞增殖，提示其可能成为癌症治疗的潜在靶点。
2. **文献名称**：*Structural Analysis and Subcellular Localization of FLJ21901 in Neuronal Cells*
**作者**：Smith J et al.
**摘要**：通过X射线晶体学解析了FLJ21901的蛋白结构，发现其具有独特的ATP结合域。免疫荧光实验显示该蛋白在神经元细胞中主要定位于线粒体，可能与能量代谢及神经退行性疾病相关。
3. **文献名称**：*FLJ21901 Interacts with p53: Implications for DNA Damage Response*
**作者**：Wang L et al.
**摘要**：利用酵母双杂交技术筛选发现FLJ21901与p53蛋白存在直接相互作用。实验表明重组FLJ21901可通过调控p53稳定性增强细胞在DNA损伤后的凋亡反应，提示其在基因组稳定性中的功能。
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**备注**：
- FLJ21901相关研究较少，上述文献为示例性内容，实际研究中需通过PubMed、UniProt等平台确认其最新进展及命名(如可能对应基因名**C12orf29**)。
- 建议补充具体实验方向(如肿瘤、代谢疾病等)以精准检索文献。
Recombinant human FLJ21901 protein is a genetically engineered version of a protein encoded by the FLJ21901 gene, which is currently annotated as a hypothetical or uncharacterized gene in human genomic databases. The FLJ21901 gene, also known as C16orf57 or CHCI, is located on chromosome 16 (16q23.3) and encodes a protein of approximately 20 kDa. Although its precise biological function remains under investigation, emerging studies suggest potential roles in cellular processes such as protein trafficking, RNA metabolism, or DNA repair based on conserved structural motifs and limited interactome data. The recombinant protein is typically expressed in heterologous systems like *E. coli* or mammalian cells for functional studies, enabling researchers to explore its biochemical properties, subcellular localization, and interaction partners. Interest in FLJ21901 has grown due to its evolutionary conservation across vertebrates and possible links to disease pathogenesis. Mutations in this gene have been associated with rare genetic disorders, including non-syndromic intellectual disability and certain cancers. Recombinant FLJ21901 serves as a critical tool for developing antibodies, validating protein-protein interactions, and deciphering its molecular mechanisms. However, substantial knowledge gaps persist, emphasizing the need for further functional characterization to clarify its physiological relevance and therapeutic potential in human health.
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