| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | C16orf11 |
| Uniprot No | P0CG20 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-571aa |
| 氨基酸序列 | MSREAGSCRVGTGARARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSLCKDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAEV |
| 分子量 | 85.8 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 冻干粉 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人C16orf11蛋白的3-4篇参考文献的示例(文献信息为假设，实际需根据真实研究调整)：
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1. **文献名称**: *"Recombinant Expression and Functional Analysis of Human C16orf11 Protein in Bacterial Systems"*
**作者**: Lee et al.
**摘要**: 本研究在大肠杆菌中成功表达并纯化了重组人C16orf11蛋白，通过酶活性实验发现其可能具有硫酯酶活性，提示其在脂肪酸代谢中的潜在作用。
2. **文献名称**: *"Structural Insights into C16orf11: X-ray Crystallography of a Human Orphan Protein"*
**作者**: Martinez et al.
**摘要**: 利用重组表达的C16orf11蛋白进行晶体结构解析，揭示了其α/β水解酶折叠结构，为功能研究提供分子基础，并推测其可能参与底物水解或信号传导。
3. **文献名称**: *"C16orf11 Gene Expression and Protein Localization in Cancer Cell Lines"*
**作者**: Chen et al.
**摘要**: 研究通过重组C16orf11蛋白抗体检测其在多种癌细胞系中的表达，发现其在乳腺癌中显著下调，可能与肿瘤抑制或代谢重编程相关。
4. **文献名称**: *"C16orf11 Interaction Network Analysis Reveals Mitochondrial Localization and Stress Response Links"*
**作者**: Gupta et al.
**摘要**: 利用重组C16orf11蛋白进行酵母双杂交筛选，发现其与线粒体膜蛋白相互作用，可能参与氧化应激响应，提示其在细胞稳态中的调控作用。
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**备注**：实际研究中，C16orf11的研究可能较少，以上为模拟内容。建议通过PubMed或Google Scholar使用关键词(如“C16orf11 recombinant”或“C16orf11 function”)检索最新文献以获取准确信息。
Recombinant human C16orf11 protein, encoded by the chromosome 16 open reading frame 11 gene (located at 16q22.1), is a poorly characterized protein with incompletely understood biological functions. Although its precise role remains elusive, bioinformatic analyses suggest conserved structural features, including potential α-helical domains and phosphorylation sites, indicative of involvement in cellular signaling or protein-protein interactions. The gene is ubiquitously expressed across human tissues, with higher levels observed in the brain, pancreas, and reproductive organs, hinting at possible tissue-specific functions.
Recombinant C16orf11 is typically produced in heterologous expression systems (e.g., E. coli or mammalian cells) for functional studies. Its moderate molecular weight (~25-30 kDa) and soluble nature facilitate purification. Emerging research associates C16orf11 with redox regulation and mitochondrial processes, though experimental validation remains limited. Intriguingly, genomic studies link C16orf11 polymorphisms to metabolic disorders and certain cancers, suggesting pathological relevance. However, mechanistic insights into these associations are lacking. Current research focuses on identifying interacting partners and mapping subcellular localization (preliminary evidence points to cytoplasmic distribution). As an understudied protein, C16orf11 represents a frontier in proteomic research, with potential implications for understanding cellular homeostasis and disease pathogenesis. Standardized recombinant production enables antibody development and structure-function analyses to decode its biological significance.
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