| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Zinc finger protein 225 |
| Entrez GeneID | 7768; |
| WB Predicted band size | 82kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ZNF225. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ZNF225抗体的3篇参考文献的示例(注：以下内容为模拟示例，实际文献可能需要进一步验证或补充)：
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1. **文献名称**：*"ZNF225: A Novel Zinc Finger Protein Involved in Transcriptional Repression"*
**作者**：Chen L, Wang Y, et al.
**摘要**：本研究利用定制的小鼠多克隆抗体(针对ZNF225的C端结构域)探讨了ZNF225在基因调控中的作用。通过免疫沉淀和染色质免疫共沉淀(ChIP)实验，发现ZNF225通过与特定DNA序列结合抑制靶基因表达，可能参与肿瘤抑制通路。
2. **文献名称**：*"Development and Application of a Polyclonal Antibody for Detecting ZNF225 in Human Tissues"*
**作者**：Kim S, Park JH, et al.
**摘要**：研究团队开发并验证了一种兔源多克隆抗体，用于检测人组织样本中的ZNF225蛋白。Western blot和免疫组化结果显示，ZNF225在心脏和肾脏中高表达，提示其在器官发育中的潜在功能。
3. **文献名称**：*"ZNF225 Antibody Screening in Epigenetic Modifications: Implications for Autoimmune Diseases"*
**作者**：Rodriguez M, Gupta R, et al.
**摘要**：本文利用商业化的ZNF225单克隆抗体(货号：Abcam ab12XXX)，研究了该蛋白在表观遗传修饰中的作用。实验表明，ZNF225可能通过组蛋白去乙酰化酶(HDAC)复合物调控免疫相关基因，与系统性红斑狼疮(SLE)存在关联。
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**注意**：以上文献为模拟生成，实际研究中可能需通过PubMed、Google Scholar或抗体厂商官网(如Thermo Fisher、Abcam)查询具体信息。若研究较少，可参考涉及ZNF家族其他成员(如ZNF224、ZNF226)的抗体应用文献作为补充。
ZNF225 (Zinc Finger Protein 225) is a member of the zinc finger protein family, characterized by conserved zinc finger domains that facilitate DNA or RNA binding, enabling roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. Predominantly expressed in various tissues, ZNF225 is implicated in modulating gene expression networks, though its precise biological functions remain under investigation. Emerging studies suggest potential involvement in cancer progression, immune responses, and developmental processes, with dysregulation linked to tumorigenesis or inflammatory diseases.
ZNF225 antibodies are immunological tools designed to detect and quantify the ZNF225 protein in experimental settings. These antibodies are typically generated using immunogenic peptides or recombinant protein fragments unique to ZNF225. ensuring specificity. Validated for applications like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and chromatin immunoprecipitation (ChIP), they enable researchers to study ZNF225's expression patterns, subcellular localization, and interactions. High-quality antibodies are essential for elucidating ZNF225's mechanistic roles, particularly in disease contexts. Commercial ZNF225 antibodies often undergo rigorous validation (e.g., knockout/knockdown controls) to confirm target specificity. As research progresses, these antibodies may serve as critical reagents for diagnostic or therapeutic development, particularly in oncology and molecular pathology.
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