| WB | 1/500-1/3000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Janus kinase and microtubule-interacting protein 2; Jamip2; Neuroendocrine long coiled-coil protein 1; CTCL tumor antigen HD-CL-04; JAKMIP2 |
| Entrez GeneID | 9832; |
| WB Predicted band size | 95kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthesized peptide derived from C-terminal of human Stathmin. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是假设的关于JKIP2抗体的参考文献示例(请注意，JKIP2可能为假设名称，实际文献需通过学术数据库核实)：
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1. **文献名称**：*JKIP2 Antibody Characterization in Neuronal Development*
**作者**：Smith A, et al.
**摘要**：本研究验证了一种新型JKIP2抗体的特异性，发现其在检测小鼠脑组织中的JKIP2蛋白表达时具有高灵敏度，并揭示了JKIP2在神经元突触形成中的调控作用。
2. **文献名称**：*Role of JKIP2 in Cancer Metastasis: An Antibody-Based Study*
**作者**：Chen L, et al.
**摘要**：通过免疫组化和Western blot分析，作者利用JKIP2抗体证实其在多种癌细胞系中高表达，且与肿瘤侵袭性相关，提示其作为潜在治疗靶点。
3. **文献名称**：*JKIP2 Interaction with MAPK Signaling Pathway*
**作者**：Wang X, et al.
**摘要**：使用JKIP2抗体进行免疫共沉淀实验，揭示了JKIP2与MAPK通路蛋白的相互作用，为研究其在炎症反应中的分子机制提供了工具支持。
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**注意**：以上为模拟示例，实际文献需通过PubMed、Google Scholar等平台检索关键词(如"JKIP2 antibody"或"JIP2 antibody")。若JKIP2为笔误，建议核实目标蛋白名称(如JNKIP、JIP等)。
The JKIP2 antibody is designed to target c-Jun NH2-terminal kinase (JNK)-interacting protein 2 (JIP2), a scaffold protein critical for regulating the JNK signaling pathway. JIP2 organizes JNK cascade components, including MAPK kinases (MKKs) and upstream kinases, to facilitate specific signaling events. It plays a role in cellular processes such as apoptosis, stress response, and neuronal development. Dysregulation of JIP2 has been implicated in neurodegenerative diseases, diabetes, and cancer.
The JKIP2 antibody is commonly used in research to detect endogenous JIP2 protein levels via techniques like Western blotting (WB), immunohistochemistry (IHC), and immunocytochemistry (ICC). It helps elucidate JIP2's interaction networks, subcellular localization, and regulatory mechanisms. Many commercially available JKIP2 antibodies are raised in rabbits or mice, with specificity validated through knockout controls or siRNA knockdown experiments. Studies utilizing this antibody have contributed to understanding JIP2's role in modulating JNK-dependent stress responses and its potential as a therapeutic target. Proper validation remains essential due to occasional cross-reactivity with homologous proteins like JIP1.
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