Rabbit Polyclonal DANREactba Antibody

The DANRE (Danio rerio) actba antibody is a research tool designed to target the β-actin protein (encoded by the *actba* gene) in zebrafish. β-actin, a highly conserved cytoskeletal protein, is crucial for cell structure, motility, and intracellular transport. In zebrafish models, β-actin serves as a common loading control in Western blotting and immunohistochemistry due to its constitutive expression across tissues. The DANRE actba antibody is often used to validate gene editing (e.g., CRISPR knockouts), assess tissue-specific protein expression, or monitor developmental changes in zebrafish embryos and adults. Its specificity for zebrafish β-actin helps minimize cross-reactivity issues in comparative studies involving other model organisms. Researchers also apply this antibody in toxicology, developmental biology, and disease modeling, leveraging zebrafish's transparency and rapid embryogenesis. Commercial variants are typically raised in rabbits or mice, with validation across zebrafish-specific assays. While β-actin antibodies are widely available for mammals, the DANRE actba antibody addresses the need for species-specific reagents in zebrafish research, ensuring accuracy in studies where cross-species reactivity could confound results.