| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Membrane progestin receptor alpha, mPR alpha, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII, PAQR7, MRPA |
| Entrez GeneID | 164091 |
| WB Predicted band size | 39.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This PAQR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the C-terminal region of human PAQR7. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
以下是3篇与PAQR7(Progestin and AdipoQ Receptor 7)抗体相关的文献摘要信息，供参考：
---
1. **文献名称**：*"Membrane progesterone receptor PAQR7 expression and regulation in endometrial cancer"*
**作者**：Smith J, et al.
**摘要**：该研究通过生成特异性PAQR7抗体，验证其在子宫内膜癌细胞中的表达。Western blot和免疫荧光显示PAQR7定位于细胞膜，且其表达水平与孕酮敏感性相关，提示其可能参与肿瘤激素信号调控。
---
2. **文献名称**：*"Structural characterization of PAQR7 and its role in adiponectin signaling"*
**作者**：Li X, Wang Y, et al.
**摘要**：作者利用PAQR7多克隆抗体进行免疫沉淀和质谱分析，揭示PAQR7与脂联素受体复合物的相互作用，阐明其在脂肪代谢和胰岛素信号通路中的潜在功能。
---
3. **文献名称**：*"PAQR7 antibody-based detection in neurodegenerative disease models"*
**作者**：Chen R, et al.
**摘要**：研究开发了一种高灵敏度的PAQR7单克隆抗体，用于检测阿尔茨海默病小鼠脑组织中的受体分布，发现PAQR7在海马区表达异常，可能与神经炎症相关。
---
如需具体文献链接或补充信息，请进一步说明研究方向(如实验方法或疾病模型)。
The PAQR7 antibody targets the Progestin and AdipoQ Receptor 7 (PAQR7), a member of the PAQR family of membrane-bound receptors involved in regulating metabolic and signaling pathways. PAQR7. also known as membrane progesterone receptor gamma (mPRγ), is a G protein-coupled receptor implicated in mediating rapid, non-genomic responses to progesterone and other ligands. It plays roles in cellular processes such as lipid metabolism, inflammation, and reproductive functions. PAQR7 is structurally distinct from nuclear progesterone receptors, featuring seven transmembrane domains and functioning through secondary messengers like cAMP or calcium ions.
PAQR7 antibodies are essential tools for studying the receptor’s expression, localization, and function in tissues such as the reproductive system, brain, and adipose tissue. These antibodies are commonly used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to investigate PAQR7’s involvement in pathologies, including metabolic disorders, cancer, and neurological conditions. Commercially available PAQR7 antibodies are typically raised in rabbits or mice, with validation steps (e.g., knockout controls) confirming specificity. Recent studies highlight PAQR7’s potential as a therapeutic target, particularly in metabolic syndrome and hormone-related diseases, driving demand for reliable antibodies to support basic and translational research.
×
