Rabbit Polyclonal DANREhoxd11a Antibody

The DANRE hoxd11a antibody is a specialized tool used to study the expression and function of the hoxd11a gene in zebrafish (*Danio rerio*). Hox genes, including hoxd11a, are evolutionarily conserved transcription factors critical for embryonic development, particularly in establishing body segmentation and limb or fin patterning along the anterior-posterior axis. In zebrafish, hoxd11a is implicated in the development of paired fins and axial skeleton, reflecting its role in vertebrate limb evolution. The antibody targets the Hoxd11a protein, enabling researchers to visualize its spatial and temporal distribution during embryogenesis. Typically produced in rabbits or mice using immunogenic peptides or recombinant proteins, this antibody is validated for applications like immunohistochemistry, Western blotting, and whole-mount in situ hybridization. Its development supports mechanistic studies on hoxd11a’s regulatory networks, gene knockout phenotypes, and evolutionary comparisons with orthologs in other species. By facilitating precise detection, the DANRE hoxd11a antibody has become essential for dissecting the molecular basis of developmental processes and genetic perturbations in zebrafish models.