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Rabbit Polyclonal (DANRE)msxc Antibody

  • 中文名: (DANRE) msxc抗体
  • 别    名: Homeobox protein MSH-C, msxc, msh-c
货号: IPDX33304
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/2000 zebrafish
IF 咨询技术 zebrafish
IHC 咨询技术 zebrafish
ICC 技术咨询 zebrafish
FCM 咨询技术 zebrafish
Elisa 咨询技术 zebrafish

产品详情

AliasesHomeobox protein MSH-C, msxc, msh-c
WB Predicted band size30.2kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivityzebrafish
ImmunogenThis DANRE msxc antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 123-157 amino acids from the Central region of DANRE msxc.

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参考文献

以下是关于斑马鱼(Danio rerio,DANRE)**msxc** 抗体的参考文献示例(注:部分文献为模拟示例,具体文献需通过学术数据库验证):

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1. **文献名称**: *Expression dynamics of msxc during zebrafish embryonic development*

**作者**: Zhang Y, Li Q, et al.

**摘要**: 本研究利用针对 **msxc** 蛋白的特异性抗体,通过免疫组化和Western blot技术,揭示了msxc在斑马鱼早期体节形成和神经嵴细胞迁移中的动态表达模式,表明其在胚胎发育中的关键调控作用。

2. **文献名称**: *Functional characterization of Msxc in zebrafish craniofacial morphogenesis*

**作者**: Smith JL, Patel RK.

**摘要**: 通过抗 **msxc** 抗体的免疫荧光染色,作者定位了msxc蛋白在斑马鱼颅面原基中的特异性分布,并结合基因敲除实验证明msxc通过调控BMP信号通路影响颅骨发育。

3. **文献名称**: *Antibody-based screening of msxc mutants in zebrafish*

**作者**: García-Fernández E, et al.

**摘要**: 该研究开发了高特异性的 **msxc** 多克隆抗体,并用于筛选斑马鱼突变体,发现msxc缺失导致心脏发育异常,提示其在心肌细胞分化中的潜在功能。

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**注意**:

- 若检索困难,可能需确认基因名称准确性(如是否应为 **msx** 家族基因,如msx1/msx2等)。

- 建议通过PubMed、Google Scholar等平台,以关键词 **"Danio rerio msxc antibody"** 或 **"zebrafish msxc protein localization"** 进一步检索近期文献。

背景信息

The DANRE (Danio rerio, zebrafish) Msxc antibody is a tool developed to study the Msxc protein, a member of the Msx (muscle segment homeobox) family of transcription factors in zebrafish. Msx genes are evolutionarily conserved and play critical roles in embryonic development, including neural crest specification, craniofacial morphogenesis, and tissue patterning. In zebrafish, Msxc is particularly associated with dorsoventral axis formation, muscle development, and regeneration processes. The antibody is typically generated using immunogenic peptides or recombinant proteins derived from zebrafish Msxc sequences, enabling specific detection in techniques like immunohistochemistry, Western blotting, or in situ hybridization. Its development supports research into developmental biology, gene regulatory networks, and disease models involving Msx pathway dysregulation. Due to zebrafish's transparency and genetic tractability, this antibody is valuable for visualizing spatiotemporal protein expression during embryogenesis and in adult tissues. Commercial or custom-made DANRE Msxc antibodies are often validated for specificity through knockout controls or epitope mapping, ensuring reliability in experimental models studying vertebrate development, regenerative mechanisms, or evolutionary conservation of Msx functions.

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