关键信息
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基因名
OVOL3
- 应用
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00110
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表达区间
1-214aa
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分子量
31.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
OVOL3 (ovalbumin upstream promoter-transcription factor 3) is a member of the OVOL family of proteins, which are transcription factors involved in various biological processes, including embryonic development, cell differentiation, and epithelial homeostasis. Recent studies have highlighted the role of OVOL3 in regulating critical pathways associated with cancer progression, particularly in certain types of epithelial cancers. Its expression has been linked to mesenchymal-to-epithelial transition (MET), a key process in tumorigenesis that influences metastasis and the response to therapies. Additionally, OVOL3 has been implicated in maintaining pluripotency and self-renewal in stem cells, indicating its importance in developmental biology. Given its diverse functional roles, researchers have focused on the recombinant expression of OVOL3 to investigate its biological activities in vitro and in vivo. This research aims to elucidate the molecular mechanisms underlying OVOL3's function and its potential as a therapeutic target in cancer treatment. Understanding the dynamics of OVOL3 could pave the way for novel cancer therapies that exploit its regulatory functions and improve patient outcomes. As a result, producing OVOL3 as a recombinant protein offers valuable insights into its structure and function, providing a foundation for further studies in disease modeling and drug discovery.
