| WB | 1/2000 | zebrafish |
| IF | 咨询技术 | zebrafish |
| IHC | 咨询技术 | zebrafish |
| ICC | 技术咨询 | zebrafish |
| FCM | 咨询技术 | zebrafish |
| Elisa | 咨询技术 | zebrafish |
| WB Predicted band size | 22.2kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | zebrafish |
| Immunogen | This DANRE soga3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-229 amino acids from DANRE soga3b. |
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以下是3篇关于斑马鱼(Danio rerio)soga3b抗体的虚拟参考文献示例，基于常见研究场景合理推测：
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1. **文献名称**：*SOGA3B regulates early neural crest migration in zebrafish via Wnt signaling modulation*
**作者**：Li, X., & Zhang, Y.
**摘要**：本研究利用特异性soga3b抗体进行全胚胎免疫荧光染色，发现SOGA3B蛋白在斑马鱼神经嵴细胞迁移前体高表达。通过基因敲降实验证实，soga3b缺失导致Wnt/β-catenin通路活性异常，进而影响神经嵴细胞的定向迁移。
2. **文献名称**：*Characterization of a novel polyclonal antibody against zebrafish Soga3b for developmental studies*
**作者**：Müller, R., et al.
**摘要**：文章报道了一种新型兔源多克隆soga3b抗体的制备与验证。通过Western blot和免疫组化证实其特异性，并在斑马鱼原肠胚形成阶段检测到SOGA3B在脊索区域的动态表达，提示其在体轴形成中的潜在作用。
3. **文献名称**：*Soga3b interacts with cytoskeletal proteins in zebrafish cardiomyocytes revealed by co-immunoprecipitation*
**作者**：Tanaka, H., et al.
**摘要**：利用soga3b抗体进行免疫共沉淀实验，发现斑马鱼心肌细胞中SOGA3B与α-actinin和微管蛋白存在物理相互作用。功能研究表明，soga3b敲除导致心脏收缩力下降，提示其通过细胞骨架调控影响心脏发育。
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注：上述文献为假设性示例，实际研究中需通过学术数据库(如PubMed、Web of Science)检索真实文献。若需具体文章，建议结合soga3b基因的官方命名(如HGNC符号)及研究领域(如发育生物学、心血管疾病模型)进一步筛选。
The DANRE (Danio rerio) soga3b antibody is a specialized tool developed to study the SOGA3B protein in zebrafish, a widely used model organism for developmental biology and genetic research. SOGA3B (Suppressor of Glucose, Autophagy-associated 3B) is implicated in cellular processes such as glucose metabolism, autophagy, and intracellular signaling. In zebrafish, it plays a role in embryonic development, particularly in neurogenesis and organogenesis, with potential links to conserved pathways like Notch signaling.
This antibody is typically generated in host species (e.g., rabbit or mouse) using immunogenic peptides or recombinant proteins derived from zebrafish SOGA3B. It enables detection and localization of endogenous SOGA3B via techniques like immunohistochemistry, Western blotting, or immunofluorescence. Validated for specificity in zebrafish tissues, it aids in exploring protein expression dynamics during development or under experimental conditions (e.g., metabolic stress). Researchers utilize it to investigate SOGA3B's functional roles in developmental defects, metabolic disorders, or disease models, leveraging zebrafish's genetic tractability and transparency for in vivo studies. Its application contributes to understanding conserved molecular mechanisms across vertebrates, bridging basic research and translational insights.
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