Rabbit Polyclonal MouseHoxb1 Antibody

The mouse Hoxb1 antibody is a specialized tool used to detect and study the Hoxb1 protein, a member of the Hox gene family critical for embryonic development. Hox genes encode transcription factors that regulate body patterning along the anterior-posterior axis, with Hoxb1 specifically playing a key role in hindbrain segmentation, particularly in rhombomere 4 (r4), and in the development of cranial nerves and facial motor neurons. Produced in species such as rabbits or mice, this antibody is typically validated for applications like Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), or chromatin immunoprecipitation (ChIP). It aids in investigating Hoxb1's expression dynamics during embryogenesis, its regulatory mechanisms in neural crest cell migration, and its potential involvement in congenital disorders. Researchers often verify its specificity using knockout controls or peptide-blocking assays. The antibody serves as a vital reagent in developmental biology, enabling insights into gene function, tissue-specific patterning, and molecular pathways linked to craniofacial or neurological abnormalities.