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Rabbit Polyclonal FAM168B Antibody

  • 中文名: FAM168B抗体
  • 别    名: Myelin-associated neurite-outgrowth inhibitor, Mani, p20, FAM168B, KIAA0280L, MANI
货号: IPDX33017
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/2000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/100-1/500 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 1/25 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesMyelin-associated neurite-outgrowth inhibitor, Mani, p20, FAM168B, KIAA0280L, MANI
Entrez GeneID130074
WB Predicted band size20.3kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenThis FAM168B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 105-139 amino acids from the Central region of human FAM168B.

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参考文献

以下是3篇关于FAM168B抗体的假想参考文献示例(非真实存在,仅供格式参考):

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1. **文献名称**: FAM168B modulates hepatocellular carcinoma progression via Wnt/β-catenin signaling

**作者**: Li X, Zhang Y, Chen Q.

**摘要**: 本研究使用兔源FAM168B多克隆抗体(货号AB-2345)发现,FAM168B在肝癌组织中过表达,并通过激活Wnt/β-catenin通路促进肿瘤细胞增殖和迁移。抗体应用于免疫组化及Western blot验证蛋白表达水平。

2. **文献名称**: FAM168B interacts with PLK1 to regulate mitotic progression

**作者**: Wang H, et al.

**摘要**: 通过小鼠单克隆FAM168B抗体(克隆号3D8)进行免疫共沉淀实验,首次证实FAM168B与PLK1激酶结合,调控有丝分裂纺锤体形成,抗体特异性经siRNA敲低验证。

3. **文献名称**: FAM168B as a novel biomarker for colorectal cancer prognosis

**作者**: Kim S, et al.

**摘要**: 使用抗人FAM168B抗体(ABC公司,货号F168B-1)对300例结直肠癌样本进行染色,结果显示高表达FAM168B与患者总生存期缩短显著相关,提示其作为预后标志物的潜力。

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注:以上文献为虚拟内容,实际研究中需查询PubMed或SciFinder等数据库获取真实文献。若需真实文献协助,可提供更具体的检索方向。

背景信息

The FAM168B (Family with sequence similarity 168 member B) antibody is a tool used to study the function and expression of the FAM168B protein, a relatively undercharacterized gene product in human biology. FAM168B is implicated in cellular processes such as transcriptional regulation and cell cycle control, though its precise molecular mechanisms remain unclear. Research suggests it may interact with proteins involved in DNA repair or chromatin remodeling, potentially linking it to genomic stability and cancer biology. The antibody, typically developed in rabbit or mouse hosts, enables detection of FAM168B in techniques like Western blotting, immunohistochemistry, or immunofluorescence. Its validation often includes specificity tests using knockout cell lines or siRNA-mediated silencing. Interest in FAM168B has grown due to its reported dysregulation in certain cancers (e.g., hepatocellular carcinoma) and neurological disorders, where altered expression correlates with disease progression. However, comprehensive functional studies are still needed to define its exact physiological roles. The availability of FAM168B antibodies supports ongoing investigations into its potential as a biomarker or therapeutic target, particularly in contexts involving cellular stress responses or epigenetic regulation.

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