Rabbit Polyclonal OR5M9 Antibody

OR5M9 is an olfactory receptor (OR) belonging to the G protein-coupled receptor (GPCR) superfamily, primarily involved in odorant detection. Antibodies targeting OR5M9 are essential tools for studying its expression, localization, and function in both olfactory and non-olfactory tissues. While ORs are classically associated with smell perception, emerging research suggests roles in non-sensory tissues, such as the testes, brain, and certain cancers, implicating OR5M9 in processes like cell migration or disease progression. Commercial OR5M9 antibodies are typically polyclonal, raised in rabbits or mice, and validated for applications including Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Specificity is confirmed via knockout controls or peptide blocking assays. Studies using these antibodies have revealed OR5M9’s presence in tissues beyond the nasal epithelium, sparking interest in its physiological or pathological roles. However, research remains limited compared to other ORs, partly due to challenges in characterizing OR ligand specificity and signaling pathways. OR5M9 antibodies also aid in exploring gene regulation, interactions with downstream effectors, and potential therapeutic targeting. Researchers should verify antibody compatibility with their experimental models, as cross-reactivity across species may vary. Overall, OR5M9 antibodies provide critical insights into the expanding biological significance of olfactory receptors.