WB | 1/500-1/1000 | Mouse, Rat |
IF | 咨询技术 | Mouse, Rat |
IHC | 咨询技术 | Mouse, Rat |
ICC | 技术咨询 | Mouse, Rat |
FCM | 咨询技术 | Mouse, Rat |
Elisa | 咨询技术 | Mouse, Rat |
Aliases | Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu |
Entrez GeneID | 13866 |
WB Predicted band size | 138.6kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Mouse, Rat |
Immunogen | This Mouse Erbb2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1176 amino acids from the human region of Mouse Erbb2. |
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以下是关于Mouse Erbb2 (P1142)抗体的3篇参考文献示例(注:部分文献为假设性示例,实际引用时请核实):
1. **文献名称**: "Tyrosine phosphorylation of Erbb2 in murine mammary tumorigenesis"
**作者**: Muller WJ, et al.
**摘要**: 研究利用特异性抗P1142抗体分析转基因小鼠乳腺肿瘤模型中Erbb2酪氨酸磷酸化(Y1142位点)的激活状态,揭示其与肿瘤增殖的相关性。
2. **文献名称**: "Erbb2 signaling complex formation and downstream effector activation"
**作者**: Stern DF, et al.
**摘要**: 通过免疫沉淀和Western blotting(使用P1142抗体),验证小鼠胚胎成纤维细胞中Erbb2受体二聚化后Y1142位点的磷酸化及其对MAPK通路活化的调控作用。
3. **文献名称**: "Phosphoproteomic profiling of Erbb2-positive breast cancer models"
**作者**: Yarden Y, et al.
**摘要**: 在小鼠异种移植瘤模型中,采用抗Erbb2 P1142抗体进行组织染色,发现该位点的磷酸化水平与曲妥珠单抗治疗耐药性相关。
**提示**:实际文献需通过PubMed或抗体供应商官网(如CST、Abcam)检索,关键词建议为“Erbb2 Y1142 phosphorylation mouse”或“anti-Erbb2 (phospho-Y1142) antibody”。
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