| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Trafficking protein particle complex subunit 13, TRAPPC13, C5orf44 |
| Entrez GeneID | 80006 |
| WB Predicted band size | 46.5kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This C5orf44 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of human C5orf44. |
+ +
以下是关于C5orf44(N-term)抗体的3篇示例参考文献(注：文献为虚构示例，实际需通过数据库验证)：
1. **文献名称**：*Characterization of C5orf44 Expression in Neural Tissues Using a Novel N-terminal Antibody*
**作者**：Smith A, et al. (2018)
**摘要**：本研究开发了一种针对C5orf44蛋白N端表位的特异性抗体，通过Western blot和免疫组化验证其在人脑组织中的表达，发现C5orf44在神经元中高表达，可能与突触功能相关。
2. **文献名称**：*C5orf44 N-terminal Antibody Reveals Elevated Expression in Colorectal Cancer*
**作者**：Zhang L, et al. (2020)
**摘要**：利用C5orf44 N端抗体对结直肠癌组织进行检测，发现其蛋白表达水平显著高于正常组织，且与患者生存率负相关，提示其可能作为癌症生物标志物。
3. **文献名称**：*Proteomic Analysis of C5orf44 Interactions via Immunoprecipitation Using an N-term Antibody*
**作者**：Kim H, et al. (2021)
**摘要**：通过C5orf44 N端抗体进行免疫共沉淀实验，鉴定了与C5orf44相互作用的多个线粒体相关蛋白，表明其在细胞能量代谢中潜在的作用。
**提示**：实际研究中关于C5orf44的文献较少，建议通过PubMed或Google Scholar以“C5orf44 antibody”或“C5orf44 N-terminal”为关键词检索最新文献，并验证抗体特异性及研究背景。
The C5orf44 (Chromosome 5 Open Reading Frame 44) gene, located on 5q31.1. encodes a protein of unknown function, though its conserved domains suggest potential roles in protein-protein interactions or signaling pathways. It is ubiquitously expressed across tissues, with elevated levels observed in brain, testis, and certain cancers. The C5orf44 (N-term) antibody specifically targets the N-terminal region of the protein (approximately amino acids 1-150), a domain predicted to contain structural motifs critical for its putative function.
This polyclonal antibody, typically raised in rabbits using synthetic peptides or recombinant protein fragments, enables detection of C5orf44 in applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Its development stems from growing interest in C5orf44's potential links to diseases, particularly cancer. Studies report altered C5orf44 expression in glioblastoma, colorectal carcinoma, and prostate cancer, suggesting biomarker or therapeutic target potential. However, functional studies remain limited, and the antibody serves primarily as a tool to map expression patterns and subcellular localization (predominantly cytoplasmic).
Validation often includes knockout cell line controls to confirm specificity. Despite its unclear biological role, C5orf44 research highlights the importance of characterizing understudied genes, with this antibody providing a foundational reagent for exploratory studies in oncology and cellular biology. Further work is needed to elucidate its molecular interactions and disease relevance.
×
