关键信息
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基因名
XCL2
- 应用
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别名
XCL2；SCYC2；Cytokine SCM-1 beta
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UBD3
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表达区间
22-114aa
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氨基酸序列
VGSEVSHRR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
XCL2, also known as lymphotactin or SCYA4, is a chemokine that plays a crucial role in the immune system by attracting and activating lymphocytes. It is primarily produced by activated T cells and has been implicated in various immune responses, including inflammation and tissue repair. The study of recombinant XCL2 protein has garnered attention due to its potential therapeutic applications in treating immune-related disorders, such as autoimmune diseases and cancers. Understanding the structure and function of XCL2 is essential for elucidating its role in immune regulation. Researchers have developed recombinant XCL2 to investigate its signaling pathways and interactions with its receptors, particularly XCR1, which is predominantly expressed on dendritic cells and T lymphocytes. The recombinant protein allows for detailed studies on its chemotactic properties, signaling mechanisms, and the identification of downstream effects in immune cells. Additionally, XCL2's dual functionality in promoting both immune activation and regulation makes it a candidate for novel therapeutic strategies aimed at modulating immune responses. As studies continue to explore its molecular mechanisms and potential applications, recombinant XCL2 serves as a valuable tool in advancing our understanding of immune cell trafficking and developing targeted interventions for various diseases.
