Rabbit Polyclonal DANREmycl1a(N-term) Antibody

The DANRE MYCL1a (N-term) antibody is a polyclonal or monoclonal antibody specifically designed to target the N-terminal region of the MYCL1a protein in *Danio rerio* (zebrafish). MYCL1a, a member of the Myc family of transcription factors, plays critical roles in regulating cell proliferation, differentiation, and apoptosis during vertebrate development. In zebrafish, MYCL1a is implicated in early embryonic development, particularly in somitogenesis and neural crest cell migration. The antibody is commonly generated in hosts like rabbits or mice using synthetic peptides or recombinant proteins corresponding to the N-terminal epitopes of MYCL1a. It is widely utilized in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect MYCL1a expression levels and localization in zebrafish tissues or embryos. Validation typically includes knockout/knockdown controls to confirm specificity. Researchers employ this antibody to study MYCL1a's functional dynamics in developmental biology, cancer models (due to Myc family oncogenic links), and regenerative mechanisms. Its application contributes to understanding conserved regulatory pathways across vertebrates and potential translational insights into MYC-driven diseases. Commercial suppliers often provide detailed datasheets outlining its reactivity, recommended dilutions, and storage conditions.