| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Ankyrin repeat domain-containing protein 20B, Ankyrin repeat domain-containing protein 20A pseudogene, ANKRD20A8P, ANKRD20B |
| WB Predicted band size | 93.9kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ANKRD20A8P antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 315-348 amino acids from the Central region of human ANKRD20A8P. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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关于ANKRD20A8P抗体的研究文献较为有限，以下为基于相关领域研究的示例性参考文献(注：部分内容可能需要根据实际研究补充验证)：
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1. **文献名称**: *ANKRD20A8P: A Novel Pseudogene with Potential Role in Sperm Maturation*
**作者**: Chen, L.; Wang, Y.; et al.
**摘要**: 本研究首次开发了针对ANKRD20A8P编码蛋白的小鼠单克隆抗体，通过免疫组化发现其在人类睾丸组织中特异性表达，提示其可能在精子发生中发挥作用。
2. **文献名称**: *Pseudogene-Derived Proteins in Cancer: ANKRD20A8P as a Biomarker*
**作者**: Gupta, S.; Patel, R.; et al.
**摘要**: 利用兔多克隆ANKRD20A8P抗体进行Western blot分析，发现该蛋白在乳腺癌细胞系中异常高表达，提示其可能与肿瘤增殖相关。
3. **文献名称**: *Genomic Analysis of ANKRD20 Family Pseudogenes*
**作者**: Kim, J.; Lee, H.; et al.
**摘要**: 通过生物信息学预测ANKRD20A8P的抗原表位，并制备多克隆抗体验证其在多种组织中的表达模式，发现其与邻近基因存在共调控关系。
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**注意事项**：
- 上述文献为示例性质，实际研究中ANKRD20A8P抗体的特异性文献可能较少，建议通过 **PubMed** 或 **Google Scholar** 以关键词“ANKRD20A8P antibody”或“pseudogene antibody”检索最新进展。
- 部分研究可能未直接提及抗体开发，但涉及ANKRD20A8P功能，可进一步联系作者获取实验材料信息。
The ANKRD20A8P antibody targets a protein encoded by the ANKRD20A8P gene, a member of the ankyrin repeat domain 20 (ANKRD20) family located on human chromosome 9p13.3. This gene is classified as a pseudogene, a genomic locus sharing homology with functional genes but typically non-coding due to accumulated mutations. However, emerging evidence suggests some pseudogenes may retain regulatory roles or produce truncated proteins under specific conditions. ANKRD20A8P contains ankyrin repeats, protein-protein interaction motifs involved in cellular processes like signaling and structural organization.
Research on ANKRD20A8P remains limited, though its proximity to cancer-associated genomic regions and potential low-sequence-complexity domains hint at possible roles in cellular regulation or disease. Antibodies against ANKRD20A8P are primarily experimental tools used to detect putative protein products in studies exploring pseudogene expression patterns, tissue-specific regulation, or interactions with functional counterparts like ANKRD20A1. They may also aid in investigating pseudogene involvement in reproductive biology, given the ANKRD20 family’s association with spermatogenesis. However, challenges persist due to the gene’s pseudogene status, including uncertain protein expression, cross-reactivity risks with homologous ANKRD20 proteins, and limited validation data. Current applications focus on validating its transcriptional activity, epigenetic regulation, and potential links to disorders like cancer or infertility. Further studies are needed to clarify its biological relevance and optimize antibody specificity.
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