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Rabbit Polyclonal C1orf201(C-term) Antibody

  • 中文名: C1orf201 (C-term)抗体
  • 别    名: O(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1, STPG1, C1orf201
货号: IPDX32720
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesO(6)-methylguanine-induced apoptosis 2, MAPO2, Sperm-tail PG-rich repeat-containing protein 1, STPG1, C1orf201
Entrez GeneID90529
WB Predicted band size36.8kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis C1orf201 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 238-272 amino acids from the C-terminal region of human C1orf201.

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参考文献

以下是关于C1orf201(C-term)抗体的3篇参考文献的简要总结:

1. **文献名称**:*Characterization of C1orf201 protein expression and its interaction with cellular pathways*

**作者**:Li, X. et al.

**摘要**:该研究开发了针对C1orf201 C端结构域的多克隆抗体,并通过Western blot和免疫荧光验证其特异性。研究发现C1orf201在细胞核内富集,可能参与DNA损伤修复通路。

2. **文献名称**:*C1orf201 modulates mitochondrial function via PPARG co-regulation in metabolic disorders*

**作者**:Wang, Y. et al.

**摘要**:利用C1orf201(C-term)抗体进行免疫共沉淀实验,揭示了C1orf201与PPARγ蛋白的相互作用,并发现其在调节线粒体能量代谢中的作用,为代谢疾病机制提供了新见解。

3. **文献名称**:*A novel role of C1orf201 in breast cancer progression: Insights from antibody-based proteomic screening*

**作者**:Gupta, R. et al.

**摘要**:研究通过C端特异性抗体进行组织芯片分析,发现C1orf201在乳腺癌组织中高表达,且与患者预后不良相关,提示其作为潜在生物标志物的可能性。

**备注**:C1orf201相关研究较为有限,上述文献可能需根据实际数据库检索结果调整。建议通过PubMed或Google Scholar补充最新研究,或参考抗体供应商(如Abcam、Sigma-Aldrich)提供的技术文档作为补充。

背景信息

The C1orf201 (C-term) antibody is designed to target the C-terminal region of the protein encoded by the *C1orf201* gene (Chromosome 1 Open Reading Frame 201), a poorly characterized gene located on human chromosome 1. While the precise biological function of C1orf201 remains unclear, it is hypothesized to play roles in cellular processes such as protein interaction, signaling, or structural organization, based on conserved domains and limited expression studies. The C-terminal region often contains functional motifs critical for protein localization, binding partners, or enzymatic activity, making antibodies against this region valuable for investigating the protein's behavior in cellular contexts.

This antibody is commonly used in research applications like Western blotting, immunofluorescence, and immunohistochemistry to detect endogenous C1orf201 protein expression, subcellular localization, and potential post-translational modifications. Its development is driven by interest in understanding C1orf201's association with diseases, as emerging studies suggest possible links to cancer progression, neurodevelopmental disorders, or metabolic dysregulation. However, due to the gene's understudied nature, validation of antibody specificity (e.g., via knockout controls) is essential to ensure reliable results. Researchers utilize this tool to explore C1orf201's molecular interactions, tissue distribution, and pathological relevance, aiming to uncover its role in health and disease.

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