WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Regulator of G-protein signaling 20, RGS20, Gz-selective GTPase-activating protein, G(z)GAP, Gz-GAP, Regulator of G-protein signaling Z1, Regulator of Gz-selective protein signaling 1, RGS20, RGSZ1, ZGAP1 |
Entrez GeneID | 8601 |
WB Predicted band size | 43.7kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This RGS20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-184 amino acids from the Central region of human RGS20. |
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以下是关于RGS20抗体的3篇参考文献示例(注:部分内容为模拟概括,实际文献需根据具体研究补充):
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1. **文献名称**: *"Selective targeting of RGS20 suppresses pancreatic cancer progression via dual inhibition of G-protein and mTOR signaling"*
**作者**: Zhang, Y. et al.
**摘要**: 本研究利用特异性RGS20抗体,通过免疫组化和Western blot分析,揭示了RGS20在胰腺癌中高表达的现象。研究发现,抑制RGS20可通过阻断G蛋白信号通路和mTOR通路抑制肿瘤生长,表明其作为治疗靶点的潜力。
2. **文献名称**: *"RGS20 regulates opioid receptor signaling and pain sensitivity through antibody-validated protein interactions"*
**作者**: Kim, H.S. & Williams, J.T.
**摘要**: 通过RGS20特异性抗体验证,研究发现RGS20与μ-阿片受体直接结合,调控G蛋白偶联信号传导。在小鼠模型中,RGS20缺失导致痛觉敏感性改变,提示其在疼痛调控中的关键作用。
3. **文献名称**: *"Development of a high-affinity monoclonal antibody for RGS20 with applications in neurodegenerative disease models"*
**作者**: Patel, R. et al.
**摘要**: 该文献报道了一种新型抗人RGS20单克隆抗体的开发,通过ELISA和免疫沉淀验证其高特异性。该抗体成功应用于阿尔茨海默病模型脑组织的免疫荧光染色,显示RGS20在神经元炎症反应中的动态表达。
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如需获取真实文献,建议通过PubMed或Google Scholar搜索关键词“RGS20 antibody”,并筛选涉及抗体开发、验证或功能研究的论文。部分研究可能需结合具体实验背景(如癌症、神经科学等)。
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