WB | 1/1000 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 咨询技术 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 咨询技术 | Human,Mouse,Rat |
Aliases | Basic salivary proline-rich protein 4, Salivary proline-rich protein Po, Parotid o protein, Salivary proline-rich protein II-1, Protein N1, Glycosylated protein A, Peptide P-D, Proline-rich peptide IB-5, PRB4 |
WB Predicted band size | 31.3kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This PRB4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 100-130 amino acids from the Central region of human PRB4. |
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以下是3篇与PRB4抗体相关的文献摘要概览:
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1. **文献名称**:*"Characterization of a novel monoclonal antibody against PRB4 for detecting salivary proline-rich proteins"*
**作者**:Smith A, et al.
**摘要**:该研究开发了一种针对PRB4蛋白的单克隆抗体,验证了其在人唾液中的特异性。实验表明该抗体能有效识别PRB4的C端结构域,并成功用于免疫印迹和免疫组化检测,为唾液蛋白组学研究提供了新工具。
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2. **文献名称**:*"PRB4 expression in oral squamous cell carcinoma: An immunohistochemical study using anti-PRB4 antibodies"*
**作者**:Tanaka K, et al.
**摘要**:通过PRB4抗体对口腔鳞状细胞癌组织进行免疫组化分析,发现PRB4在肿瘤边缘高表达,可能与癌细胞侵袭性相关。研究提示PRB4可作为潜在肿瘤标志物,抗体特异性经Western blot验证。
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3. **文献名称**:*"Role of PRB4 in enamel formation: Insights from antibody-mediated functional blocking experiments"*
**作者**:Lee H, et al.
**摘要**:利用抗PRB4抗体阻断小鼠成釉细胞中PRB4的功能,发现其影响釉原蛋白的矿化过程,导致牙釉质发育异常。研究证实PRB4在牙釉质形成中的关键作用,抗体特异性通过敲除模型验证。
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注:PRB4(Proline-Rich Protein B4)相关研究较少,上述文献为模拟示例,实际研究中建议通过PubMed或Google Scholar以关键词检索最新成果。
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