关键信息
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基因名
GPR65
- 应用
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别名
(G-protein coupled receptor 65)(T-cell death-associated gene 8 protein)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IYL9
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表达区间
1-337aa
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分子量
40.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
GPR65, also known as the G protein-coupled receptor 65, is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in various physiological processes by mediating cellular signaling pathways. It is primarily expressed in immune cells and is implicated in the regulation of inflammation and immune responses. Research has shown that GPR65 can influence T cell differentiation and activation, making it a potential target for therapeutic interventions in autoimmune diseases and cancer. The recombinant protein of GPR65 is generated to study its structure-function relationships, signaling mechanisms, and interactions with ligands. By characterizing the recombinant GPR65, scientists aim to elucidate its role in modulating immune responses and to identify potential drug targets. Moreover, understanding how GPR65 operates at a molecular level could provide insights into the development of drugs that can selectively modulate its activity. This research is essential for translating basic scientific discoveries into clinical applications, thereby enhancing our ability to treat diseases associated with dysregulated immune function. The production and analysis of recombinant GPR65 thus represent a significant step in expanding our knowledge of GPCRs and their roles in health and disease.
