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Rabbit Polyclonal PRSS36(Center) Antibody

  • 中文名: PRSS36(Center)抗体
  • 别    名: Polyserase-2, 3421-, Polyserine protease 2, Serine protease 36, PRSS36
货号: IPDX32308
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 1/1000 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 咨询技术 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 咨询技术 Human,Mouse,Rat

产品详情

AliasesPolyserase-2, 3421-, Polyserine protease 2, Serine protease 36, PRSS36
Entrez GeneID146547
WB Predicted band size92.0kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenThis PRSS36 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the Central region of human PRSS36.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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参考文献

以下是关于PRSS36抗体的3篇参考文献示例(注:以下内容为模拟示例,实际文献需通过学术数据库验证):

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1. **文献名称**: "PRSS36 Antibody Characterization in Gastrointestinal Protease Studies"

**作者**: Wang X, et al.

**摘要**: 该研究利用PRSS36特异性抗体(Center生产),揭示了其在胃蛋白酶原活化中的作用,表明PRSS36可能参与消化系统蛋白酶的调控网络。

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2. **文献名称**: "PRSS36 as a Novel Biomarker in Endometrial Cancer"

**作者**: Lee S, et al.

**摘要**: 通过免疫组化分析(使用PRSS36抗体),研究发现PRSS36在子宫内膜癌组织中高表达,提示其可能作为癌症诊断或治疗的潜在靶点。

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3. **文献名称**: "PRSS36 Deficiency Alters Epidermal Barrier Function in Mice"

**作者**: Gonzalez F, et al.

**摘要**: 利用PRSS36敲除模型及特异性抗体,研究证明PRSS36对皮肤屏障完整性至关重要,其缺失导致角质层异常和炎症反应加剧。

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建议通过PubMed或Google Scholar以关键词“PRSS36 antibody”或“PRSS36 protease”检索最新文献以获取准确信息。

背景信息

The PRSS36 (Center) antibody is designed to detect PRSS36. a member of the trypsin-like serine protease family encoded by the PRSS36 gene. PRSS36. also known as testisin or transmembrane protease serine 36. is a glycosylphosphatidylinositol (GPI)-anchored cell surface protease predominantly expressed in male germ cells, endothelial cells, and certain epithelial tissues. It plays roles in extracellular matrix remodeling, cell signaling, and tissue homeostasis, with studies implicating it in reproductive biology, immune regulation, and cancer progression. For instance, PRSS36 is linked to sperm maturation and has been investigated in tumor microenvironments for its potential to modulate angiogenesis and metastasis. The PRSS36 (Center) antibody typically targets a central epitope within the protease domain, enabling specific detection in applications like Western blotting, immunohistochemistry, or flow cytometry. Its validation often includes knockdown/knockout controls to confirm specificity. Researchers utilize this antibody to explore PRSS36's physiological functions, pathological roles, and therapeutic implications in diseases such as infertility, inflammatory disorders, or malignancies. Commercial variants may differ in host species (e.g., rabbit, mouse) and clonality (monoclonal/polyoclonal), tailored for experimental needs.

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