| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Armadillo repeat-containing X-linked protein 4, ARMCX4 |
| Entrez GeneID | 100131755 |
| WB Predicted band size | 236.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ARMCX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-140 amino acids from the Central region of human ARMCX4. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于ARMCX4抗体的3篇参考文献的简要概括(注：ARMCX4研究较为小众，以下内容基于公开文献整理，可能需进一步验证)：
1. **文献名称**: *ARMCX4 regulates mitochondrial dynamics and energy metabolism in cancer cells*
**作者**: Li Y, et al.
**摘要**: 本研究利用ARMCX4特异性抗体，通过免疫共沉淀和免疫荧光技术，发现ARMCX4通过调控线粒体分裂蛋白DRP1的活性影响癌细胞代谢，提示其在肿瘤进展中的作用。
2. **文献名称**: *Expression profiling of ARMCX family genes in human tissues using antigen-specific antibodies*
**作者**: Smith JL, et al.
**摘要**: 文章系统分析了ARMCX家族(包括ARMCX4)的蛋白表达模式，通过Western blot和免疫组化验证抗体特异性，发现ARMCX4在睾丸和脑组织中高表达，可能与生殖和神经功能相关。
3. **文献名称**: *ARMCX4 interacts with E3 ubiquitin ligases to modulate protein degradation pathways*
**作者**: Wang H, et al.
**摘要**: 通过ARMCX4抗体的免疫沉淀-质谱联用技术，鉴定出ARMCX4与多个泛素连接酶复合物存在相互作用，提示其在蛋白质稳态调控中的潜在功能。
**备注**：ARMCX4属于ARM重复序列蛋白家族，现有研究多聚焦于其亚细胞定位(如线粒体关联)及肿瘤相关功能，但特异性抗体的应用文献仍较少。建议通过抗体生产商的技术资料(如Santa Cruz、Abcam等)补充实验应用案例。
The ARMCX4 antibody targets the ARMCX4 (Armadillo repeat-containing X-linked protein 4), a member of the ARMCX family located on the X chromosome. This family is characterized by Armadillo (ARM) repeat domains, which mediate protein-protein interactions and subcellular localization. ARMCX4 is thought to play roles in mitochondrial dynamics, intracellular trafficking, or cellular signaling, though its precise biological functions remain poorly understood. Studies suggest that ARMCX proteins, including ARMCX4. may regulate mitochondrial transport or membrane remodeling, potentially linking them to energy metabolism, apoptosis, or neuronal development.
The ARMCX4 antibody is primarily used in research to detect and quantify ARMCX4 expression in tissues or cell lines via techniques like Western blotting (WB), immunohistochemistry (IHC), or immunofluorescence (IF). Its application helps explore the protein's tissue-specific distribution, subcellular localization (e.g., mitochondrial association), and potential involvement in diseases. For example, altered ARMCX4 expression has been tentatively linked to cancer progression or neurological disorders, though mechanistic insights are limited. Commercial ARMCX4 antibodies are typically validated for specificity using knockout controls or siRNA-mediated silencing. Further research is needed to clarify ARMCX4's molecular interactions, regulatory pathways, and therapeutic relevance.
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