| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Coiled-coil domain-containing protein 91, GGA-binding partner, p56 accessory protein, CCDC91, GGABP |
| Entrez GeneID | 55297 |
| WB Predicted band size | 50.0kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This CCDC91 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human CCDC91. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
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以下是关于CCDC91抗体的参考文献示例(部分为模拟概括，供参考)：
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1. **"Characterization of a novel monoclonal antibody against CCDC91 for cancer biomarker studies"**
*Author: Li X, et al. (2020)*
摘要：该研究开发了一种针对CCDC91蛋白的单克隆抗体，验证了其在乳腺癌组织中的特异性结合能力，并发现其高表达与患者预后不良相关。
2. **"CCDC91 regulates neuronal development through endosomal trafficking: Insights from antibody-based localization"**
*Author: Smith J, et al. (2018)*
摘要：利用抗CCDC91抗体进行免疫荧光和Western blot分析，揭示了CCDC91在小鼠神经元中的亚细胞定位及其在神经突触形成中的功能。
3. **"Validation of commercial CCDC91 antibodies for functional proteomics applications"**
*Author: García-Ruiz C, et al. (2021)*
摘要：系统性评估了多种市售CCDC91抗体的特异性，发现部分抗体存在交叉反应性，为后续研究提供了抗体选择的实验依据。
4. **"CCDC91 interacts with autophagy-related proteins: A study co-immunoprecipitation using specific antibodies"**
*Author: Tanaka K, et al. (2019)*
摘要：通过抗CCDC91抗体进行免疫共沉淀实验，发现其与自噬相关蛋白LC3的相互作用，提示其在细胞自噬调控中的潜在作用。
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**注意**：以上文献信息为示例性概括，部分内容可能基于假设。实际文献需通过PubMed、Web of Science等数据库检索确认。若研究较少，可扩展至CCDC91功能研究的抗体应用描述。
The CCDC91 (Coiled-Coil Domain Containing 91) antibody is a tool used to study the protein encoded by the CCDC91 gene, which is implicated in intracellular vesicle trafficking and membrane dynamics. CCDC91. also known as GCP60 or ACBD3. interacts with Golgi-associated proteins like GOPC and plays a role in maintaining Golgi structure, protein transport, and cellular signaling. Its involvement in processes such as autophagy, lipid metabolism, and cell division has drawn attention in cancer and neurodegenerative disease research.
CCDC91 antibodies are typically developed in rabbit or mouse models using immunogenic peptide sequences specific to the protein. These antibodies are validated for applications like Western blotting, immunofluorescence, and immunoprecipitation to detect CCDC91 expression levels, localization, and interactions in various cell lines or tissues. Studies utilizing these antibodies have linked CCDC91 dysregulation to tumor progression, metabolic disorders, and impaired neuronal function, suggesting its potential as a therapeutic target or biomarker. However, challenges remain in confirming isoform specificity due to alternative splicing variants. Recent work focuses on clarifying CCDC91's mechanistic roles in membrane-associated pathways and disease pathology.
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