| WB | 1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | Putative tripartite motif-containing protein 75, Tripartite motif-containing protein 75 pseudogene, TRIM75P, TRIM75 |
| WB Predicted band size | 53.7kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This TRIM75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-324 amino acids from the Central region of human TRIM75. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
+ +
关于TRIM75抗体的直接研究目前公开文献较为有限，以下是根据相关领域推测可能相关的文献类型及示例(注：以下为模拟示例，非真实文献)：
1. **"TRIM75 regulates ubiquitination in spermatogenesis"**
- Author: Zhang et al.
- 摘要：研究TRIM75在小鼠精子形成中的作用，通过特异性抗体检测其在睾丸组织中的表达及泛素化功能。
2. **"Antibody characterization of TRIM family proteins in viral response"**
- Author: Lee & Kim
- 摘要：开发多种TRIM家族抗体(包括TRIM75)，验证其在抗病毒信号通路中的表达模式。
3. **"TRIM75 knockout mouse model reveals metabolic implications"**
- Author: Smith et al.
- 摘要：利用TRIM75抗体分析基因敲除小鼠中蛋白缺失对脂肪代谢的影响。
**实际情况说明**：经检索，目前TRIM75的针对性研究较少，可能与名称拼写(如TRIM25/TRIM21)或物种差异有关。建议进一步确认目标蛋白名称或探索其他TRIM家族成员的研究。如需协助核实文献或调整关键词，请随时告知!
The TRIM75 antibody is a research tool designed to detect and study TRIM75. a member of the tripartite motif (TRIM) protein family. TRIM proteins are characterized by their conserved RING, B-box, and coiled-coil domains, which are involved in ubiquitination, protein interactions, and cellular regulation. TRIM75. though less characterized than other TRIM members, is hypothesized to play roles in ubiquitin-mediated processes, such as protein degradation, immune signaling, and stress responses. Its expression has been noted in specific tissues, including the testes and skeletal muscle, suggesting potential functions in reproduction, muscle homeostasis, or metabolic regulation.
The TRIM75 antibody enables researchers to investigate its expression patterns, subcellular localization, and interaction partners via techniques like Western blotting, immunofluorescence, or immunoprecipitation. Current studies focus on elucidating its biological significance, particularly its links to diseases such as muscular disorders, infertility, or cancer. However, limited literature and unclear mechanistic insights highlight the need for further validation of antibody specificity and functional studies. Commercial TRIM75 antibodies are often validated for cross-reactivity and batch consistency, but researchers are advised to confirm target specificity using knockout controls. This antibody remains critical for unraveling TRIM75's role in cellular pathways and its therapeutic potential.
×
