| WB | 1/500-1/1000 | Human,Mouse,Rat |
| IF | 1/20 | Human,Mouse,Rat |
| IHC | 咨询技术 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 咨询技术 | Human,Mouse,Rat |
| Aliases | MS2; CD156; CD156a |
| Entrez GeneID | 101 |
| WB Predicted band size | Calculated MW: 89 kDa; Observed MW: 89 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthetic peptide of MS2 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
+ +
以下是关于MS2抗体的3篇参考文献，包含文献名称、作者及摘要概括：
---
1. **文献名称**：*"MS2 coat protein mutants with enhanced assembly properties"*
**作者**：Peabody DS, Lim F
**摘要**：该研究报道了MS2噬菌体衣壳蛋白的突变体设计，通过优化其组装特性，提升其在生物技术中的应用。同时验证了针对突变蛋白的特异性抗体的结合效率，为基于MS2的RNA或药物递送系统开发提供基础。
2. **文献名称**：*"A protocol for in vivo visualization of RNA using MS2-GFP system"*
**作者**：Bertrand E, Chartrand P
**摘要**：本文提出利用MS2衣壳蛋白与GFP融合标记RNA的方法，通过特异性抗体实现活细胞内RNA动态的实时追踪，为研究基因表达调控提供了重要工具。
3. **文献名称**：*"MS2-Tag system for RNA purification and imaging in mammalian cells"*
**作者**：Jiang L, Liu P
**摘要**：开发了一种基于MS2标签的RNA纯化与成像系统，通过高亲和力抗体实现靶RNA的高效富集和可视化，适用于转录组学及单分子生物学研究。
---
这些文献涵盖了MS2抗体的分子优化、活细胞RNA成像及靶向纯化等应用方向。如需具体文章链接或更多文献，可进一步通过PubMed或Google Scholar检索DOI。
The MS2 antibody is a key reagent in molecular biology, primarily targeting the capsid protein of the MS2 bacteriophage, an RNA virus infecting *E. coli*. The MS2 capsid protein, a 13.7 kDa monomer, self-assembles into an icosahedral shell to encapsidate the viral genome. Its high affinity for a specific RNA hairpin structure in the phage genome has been exploited for diverse applications.
Developed as a tool for RNA-protein interaction studies, MS2 antibodies are widely used in techniques like RNA immunoprecipitation (RIP) and fluorescence in situ hybridization (FISH) to track RNA molecules in cells. By fusing the MS2 coat protein to RNA-binding motifs, researchers can "tag" RNA of interest, enabling visualization or purification via antibody-mediated capture. The system’s specificity and stability also make it valuable in diagnostic assays, including RT-qPCR-based pathogen detection.
Additionally, MS2 antibodies play roles in phage display libraries and vaccine development, as the capsid protein is non-infectious to humans. Their commercial availability and compatibility with common detection methods (e.g., Western blot, ELISA) enhance accessibility for research. Compared to similar systems (e.g., T7 or Lambda phages), MS2 offers advantages in RNA-binding modularity and lower biosafety constraints. Overall, MS2 antibodies serve as versatile tools bridging virology, synthetic biology, and biomedical engineering.
×
