关键信息
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基因名
CNTNAP5
- 应用
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别名
Caspr5; Cell recognition molecule Caspr5
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WYK1
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表达区间
Ala25~Asp302
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分子量
38kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CNTNAP5 (Contactin Associated Protein 5) is a member of the neurexin superfamily, known for its role in the development and function of the nervous system. Recent studies have highlighted its significance in synaptic formation and neuronal signaling, making it a protein of interest in neurobiological research. Genetic variations in CNTNAP5 have been linked to several neurodevelopmental disorders, including autism spectrum disorders and intellectual disability, suggesting that disruptions in its function can have profound effects on cognitive and social behaviors. The recombinant production of CNTNAP5 protein allows for detailed investigations into its structural properties and functional mechanisms, facilitating the study of its interactions with other synaptic proteins. This research can provide insights into how CNTNAP5 contributes to the pathophysiology of neurological disorders and may lead to the identification of novel therapeutic targets. Furthermore, understanding the precise role of CNTNAP5 in synaptic transmission and plasticity can enhance our overall comprehension of brain function and development, paving the way for innovative strategies in treating neurological conditions associated with its dysregulation.
