关键信息
-
基因名
mpt63
- 应用
-
别名
16KDA immunoprotective extracellular protein Antigen MPT63
-
种属
Mycobacterium tuberculosis
-
表达系统
E. coli
-
标签
N- His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P9WIP0
-
表达区间
30-159aa
-
分子量
17.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The MPT63 protein, derived from Mycobacterium tuberculosis, has garnered significant attention in the field of tuberculosis research due to its potential role as a diagnostic and therapeutic target. Research shows that MPT63 is a lipoprotein expressed during the active growth phase of the bacterium, suggesting its involvement in the pathogenicity and immune response elicited by tuberculosis. Given the global burden of tuberculosis and the rise of multi-drug resistant strains, understanding the function and immunogenic properties of MPT63 is crucial. Studies have demonstrated that MPT63 can induce specific immune responses in infected individuals, making it a candidate for inclusion in diagnostic assays. Moreover, its nature as a virulence factor presents opportunities for vaccine development. Investigating MPT63's structural characteristics and its interaction with host immune cells could pave the way for novel strategies in tackling tuberculosis and enhancing vaccine efficacy. The ongoing research emphasizes the importance of MPT63 not only in understanding the immune evasion mechanisms of Mycobacterium tuberculosis but also in developing new tools for infection control and treatment strategies.
